COVID-19: The Potential Role of Copper and N-acetylcysteine (NAC) in a Combination of Candidate Antiviral Treatments Against SARS-CoV-2.
In Vivo
; 34(3 Suppl): 1567-1588, 2020 Jun.
Article
in English
| MEDLINE | ID: covidwho-532631
ABSTRACT
BACKGROUND:
On March 11, 2020, the World Health Organization (WHO) declared the outbreak of coronavirus disease (COVID-19) a pandemic. Since then, thousands of people have suffered and died, making the need for a treatment of severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) more crucial than ever. MATERIALS ANDMETHODS:
The authors carried out a search in PubMed, ClinicalTrials.gov and New England Journal of Medicine (NEJM) for COVID-19 to provide information on the most promising treatments against SARS-CoV-2.RESULTS:
Possible COVID-19 agents with promising efficacy and favorable safety profile were identified. The results support the combination of copper, N-acetylcysteine (NAC), colchicine and nitric oxide (NO) with candidate antiviral agents, remdesivir or EIDD-2801, as a treatment for patients positive for SARS-CoV-2.CONCLUSION:
The authors propose to study the effects of the combination of copper, NAC, colchicine, NO and currently used experimental antiviral agents, remdesivir or EIDD-2801, as a potential treatment scheme for SARS-COV-2.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Antiviral Agents
/
Pneumonia, Viral
/
Acetylcysteine
/
Ribonucleosides
/
Adenosine Monophosphate
/
Colchicine
/
Coronavirus Infections
/
Copper
/
Alanine
/
Nitric Oxide
Type of study:
Prognostic study
/
Reviews
Language:
English
Journal:
In Vivo
Journal subject:
Neoplasms
Year:
2020
Document Type:
Article
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