COVID-19 and Acute Lupus Pneumonitis: Diagnostic and Treatment Dilemma.

Kichloo, Asim; Aljadah, Michael; Albosta, Michael; Wani, Farah; Singh, Jagmeet; Solanki, Shantanu

Kichloo, Asim; Aljadah, Michael; Albosta, Michael; Wani, Farah; Singh, Jagmeet; Solanki, Shantanu.

Kichloo A; St. Mary's of Saginaw Hospital, Saginaw, MI, USA.
Aljadah M; Central Michigan University, Saginaw, MI, USA.
Albosta M; Central Michigan University, Saginaw, MI, USA.
Wani F; Central Michigan University, Saginaw, MI, USA.
Singh J; St. Mary's of Saginaw Hospital, Saginaw, MI, USA.
Solanki S; Geisinger Commonwealth School of Medicine, Scranton, PA, USA.

J Investig Med High Impact Case Rep ; 8: 2324709620933438, 2020.

Article in English | MEDLINE | ID: covidwho-535847

ABSTRACT

ABSTRACT

In this article, we present a case of a young female patient with previously diagnosed lupus pneumonitis, now with a flare and new superimposed COVID-19 infection that was treated with intravenous steroids. On computed tomography scans, she had extensive interstitial lung fibrosis in addition to a positive COVID-19 polymerase chain reaction test requiring 6 L of oxygen via nasal cannula on admission. After administration of methylprednisolone, the patient improved and was weaned off her oxygen requirements and was discharged home.

Subject(s)

Coronavirus Infections/complications; Lupus Erythematosus, Systemic/complications; Pneumonia, Viral/complications; Pneumonia/complications; Antibodies, Antinuclear/immunology; Antirheumatic Agents/therapeutic use; Betacoronavirus; COVID-19; Cardiac Tamponade; Complement C3/immunology; Complement C4/immunology; Coronavirus Infections/diagnostic imaging; Coronavirus Infections/drug therapy; Coronavirus Infections/therapy; DNA; Disease Progression; Enzyme Inhibitors/therapeutic use; Female; Fibrin Fibrinogen Degradation Products; Glucocorticoids/therapeutic use; Humans; Hydroxychloroquine/therapeutic use; Lung/diagnostic imaging; Lupus Erythematosus, Systemic/diagnostic imaging; Lupus Erythematosus, Systemic/drug therapy; Lupus Erythematosus, Systemic/immunology; Lupus Nephritis; Lymphopenia/etiology; Methylprednisolone/therapeutic use; Mycophenolic Acid/therapeutic use; Oxygen Inhalation Therapy; Pandemics; Pneumonia/diagnostic imaging; Pneumonia/immunology; Pneumonia/therapy; Pneumonia, Viral/diagnostic imaging; Pneumonia, Viral/therapy; SARS-CoV-2; Tomography, X-Ray Computed; Young Adult; COVID-19 Drug Treatment

Keywords

COVID-19; lupus; pneumonia; pneumonitis

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia / Pneumonia, Viral / Coronavirus Infections / Lupus Erythematosus, Systemic Type of study: Case report Topics: Long Covid Language: English Journal: J Investig Med High Impact Case Rep Year: 2020 Document Type: Article Affiliation country: 2324709620933438

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