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Management of critically ill patients with COVID-19 in ICU: statement from front-line intensive care experts in Wuhan, China.
Shang, You; Pan, Chun; Yang, Xianghong; Zhong, Ming; Shang, Xiuling; Wu, Zhixiong; Yu, Zhui; Zhang, Wei; Zhong, Qiang; Zheng, Xia; Sang, Ling; Jiang, Li; Zhang, Jiancheng; Xiong, Wei; Liu, Jiao; Chen, Dechang.
  • Shang Y; Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Pan C; Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
  • Yang X; Department of Critical Care Medicine, Zhejiang Provincial People's Hospital, Hangzhou Medical College, Hangzhou, China.
  • Zhong M; Department of Critical Care Medicine, Zhongshan Hospital Fudan University, Shanghai, China.
  • Shang X; Department of Critical Care Medicine, Fujian Provincial Hospital, Fujian Provincial Center for Critical Care Medicine, Fuzhou, China.
  • Wu Z; Department of Critical Care Medicine, Huadong Hospital, Shanghai, China.
  • Yu Z; Department of Critical Care Medicine, Renmin Hospital, Wuhan University, Wuhan, China.
  • Zhang W; Emergency Department, the 900th Hospital of Joint Service Corps of Chinese PLA, Fuzhou, China.
  • Zhong Q; Department of Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Zheng X; Department of Critical Care Medicine, The First Affiliated Hospital of Zhejiang University, Hangzhou, China.
  • Sang L; Department of Critical Care Medicine, The 1st Affiliated Hospital of GuangZhou Medical University, GuangZhou Institute of Respiratory Health, Guangzhou, China.
  • Jiang L; Department of Critical Care Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China.
  • Zhang J; Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Xiong W; Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Liu J; Department of Critical Care Medicine, Shanghai Jiaotong University, School of Medicine, Ruijin Hospital North, No. 197 Ruijin 2nd Road, Huangpu District, Shanghai, 201801, China.
  • Chen D; Department of Critical Care Medicine, Shanghai Jiaotong University, School of Medicine, Ruijin Hospital North, No. 197 Ruijin 2nd Road, Huangpu District, Shanghai, 201801, China. chendechangsh@hotmail.com.
Ann Intensive Care ; 10(1): 73, 2020 Jun 06.
Article in English | MEDLINE | ID: covidwho-549161
Semantic information from SemMedBD (by NLM)
1. Critical Illness PROCESS_OF Patients
Subject
Critical Illness
Predicate
PROCESS_OF
Object
Patients
2. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
3. Discussion (procedure) TREATS COVID-19
Subject
Discussion (procedure)
Predicate
TREATS
Object
COVID-19
4. Discussion (procedure) TREATS Patients
Subject
Discussion (procedure)
Predicate
TREATS
Object
Patients
5. Voting PROCESS_OF Participant
Subject
Voting
Predicate
PROCESS_OF
Object
Participant
6. Targeted Therapy NEG_TREATS COVID-19
Subject
Targeted Therapy
Predicate
NEG_TREATS
Object
COVID-19
7. Targeted Therapy NEG_TREATS Patients
Subject
Targeted Therapy
Predicate
NEG_TREATS
Object
Patients
8. Critical Illness PROCESS_OF Patients
Subject
Critical Illness
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PROCESS_OF
Object
Patients
9. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
10. Discussion (procedure) TREATS COVID-19
Subject
Discussion (procedure)
Predicate
TREATS
Object
COVID-19
11. Discussion (procedure) TREATS Patients
Subject
Discussion (procedure)
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TREATS
Object
Patients
12. Voting PROCESS_OF Participant
Subject
Voting
Predicate
PROCESS_OF
Object
Participant
13. Targeted Therapy NEG_TREATS COVID-19
Subject
Targeted Therapy
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NEG_TREATS
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COVID-19
14. Targeted Therapy NEG_TREATS Patients
Subject
Targeted Therapy
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NEG_TREATS
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Patients
ABSTRACT

BACKGROUND:

The ongoing coronavirus disease 2019 (COVID-2019) pandemic has swept all over the world, posing a great pressure on critical care resources due to large number of patients needing critical care. Statements from front-line experts in the field of intensive care are urgently needed.

METHODS:

Sixteen front-line experts in China fighting against the COVID-19 epidemic in Wuhan were organized to develop an expert statement after 5 rounds of expert seminars and discussions to provide trustworthy recommendation on the management of critically ill COVID-19 patients. Each expert was assigned tasks within their field of expertise to provide draft statements and rationale. Parts of the expert statement are based on epidemiological and clinical evidence, without available scientific evidences.

RESULTS:

A comprehensive document with 46 statements are presented, including protection of medical personnel, etiological treatment, diagnosis and treatment of tissue and organ functional impairment, psychological interventions, immunity therapy, nutritional support, and transportation of critically ill COVID-19 patients. Among them, 5 recommendations were strong (Grade 1), 21 were weak (Grade 2), and 20 were experts' opinions. A strong agreement from voting participants was obtained for all recommendations.

CONCLUSION:

There are still no targeted therapies for COVID-19 patients. Dynamic monitoring and supportive treatment for the restoration of tissue vascularization and organ function are particularly important.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Clinical Practice Guide Language: English Journal: Ann Intensive Care Year: 2020 Document Type: Article Affiliation country: S13613-020-00689-1

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Clinical Practice Guide Language: English Journal: Ann Intensive Care Year: 2020 Document Type: Article Affiliation country: S13613-020-00689-1