Effect of Environmental Conditions on SARS-CoV-2 Stability in Human Nasal Mucus and Sputum.

Matson, M Jeremiah; Yinda, Claude Kwe; Seifert, Stephanie N; Bushmaker, Trenton; Fischer, Robert J; van Doremalen, Neeltje; Lloyd-Smith, James O; Munster, Vincent J

Matson, M Jeremiah; Yinda, Claude Kwe; Seifert, Stephanie N; Bushmaker, Trenton; Fischer, Robert J; van Doremalen, Neeltje; Lloyd-Smith, James O; Munster, Vincent J.

Emerg Infect Dis ; 26(9)2020 09.

Article in English | MEDLINE | ID: covidwho-574540

ABSTRACT

ABSTRACT

We found that environmental conditions affect the stability of severe acute respiratory syndrome coronavirus 2 in nasal mucus and sputum. The virus is more stable at low-temperature and low-humidity conditions, whereas warmer temperature and higher humidity shortened half-life. Although infectious virus was undetectable after 48 hours, viral RNA remained detectable for 7 days.

Subject(s)

Betacoronavirus/genetics; Coronavirus Infections/virology; Mucus/virology; Pneumonia, Viral/virology; RNA, Viral/analysis; Sputum/virology; COVID-19; Hot Temperature; Humans; Humidity; Nasal Cavity/virology; Pandemics; RNA Stability; SARS-CoV-2

Keywords

COVID-19; SARS-CoV-2; coronavirus disease; respiratory infections; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Sputum / RNA, Viral / Coronavirus Infections / Betacoronavirus / Mucus Type of study: Experimental Studies Limits: Humans Language: English Journal subject: Communicable Diseases Year: 2020 Document Type: Article

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