Therapeutic Temperature Modulation for a Critically Ill Patient with COVID-19.
J Korean Med Sci
; 35(22): e210, 2020 Jun 08.
Article
in English
| MEDLINE | ID: covidwho-574614
ABSTRACT
We report a rapidly deteriorating coronavirus disease 2019 (COVID-19) patient, a-58-year-old woman, with severe acute respiratory distress syndrome and shock with hyperpyrexia up to 41.8°C, probably due to the cytokine storm syndrome. Considering extracorporeal membrane oxygenation (ECMO) as the last resort, we applied therapeutic temperature modulation for management of hyperpyrexia. The patient demonstrated rapid improvement in oxygenation and shock after achieving normothermia, and fully recovered from COVID-19 three weeks later. Therapeutic temperature modulation may have successfully offloaded the failing cardiorespiratory system from metabolic cost and hyperinflammation induced by hyperpyrexia. The therapeutic temperature modulation can safely be applied in a specific group of patients with cytokine storm syndrome and hyperpyrexia, which may reduce the number of patients requiring ECMO in the global medical resource shortage.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Cryotherapy
/
Coronavirus Infections
/
Fever
Type of study:
Case report
Limits:
Female
/
Humans
/
Middle aged
Language:
English
Journal:
J Korean Med Sci
Journal subject:
Medicine
Year:
2020
Document Type:
Article
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