A plea for the pathogenic role of immune complexes in severe Covid-19.

Vuitton, Dominique A; Vuitton, Lucine; Seillès, Estelle; Galanaud, Pierre

Vuitton, Dominique A; Vuitton, Lucine; Seillès, Estelle; Galanaud, Pierre.

Vuitton DA; EA 3181, Université Bourgogne Franche-Comté, Besançon, France. Electronic address: dvuitton@univ-fcomte.fr.
Vuitton L; Department of Acute and Chronic Diseases, Education, and Transplantation, Gastroenterology unit, University Hospital, Besançon, France.
Seillès E; Immuno-biology Laboratory, Établissement Français du Sang (EFS) Bourgogne Franche-Comté, Besançon, France; U1098, Inserm-EFS-Université Bourgogne Franche-Comté, Besançon, France.
Galanaud P; U996, Inflammation, Microbiome and Immunosurveillance, Inserm, Université Paris-Saclay, Clamart, France.

Clin Immunol ; 217: 108493, 2020 08.

Article in English | MEDLINE | ID: covidwho-574786

Subject(s)

Antigen-Antibody Complex/biosynthesis; Betacoronavirus/pathogenicity; Coronavirus Infections/immunology; Cytokine Release Syndrome/immunology; Immune Complex Diseases/immunology; Pneumonia, Viral/immunology; Severe Acute Respiratory Syndrome/immunology; Vasculitis/immunology; Antibodies, Viral/biosynthesis; Antigen-Antibody Complex/drug effects; Betacoronavirus/immunology; Blood Vessels/drug effects; Blood Vessels/immunology; Blood Vessels/pathology; Blood Vessels/virology; COVID-19; Complement C3/antagonists & inhibitors; Complement C3/biosynthesis; Complement Inactivating Agents/therapeutic use; Coronavirus Infections/complications; Coronavirus Infections/drug therapy; Coronavirus Infections/virology; Cytokine Release Syndrome/complications; Cytokine Release Syndrome/drug therapy; Cytokine Release Syndrome/virology; Humans; Immune Complex Diseases/complications; Immune Complex Diseases/drug therapy; Immune Complex Diseases/virology; Immunity, Humoral/drug effects; Interleukin 1 Receptor Antagonist Protein/therapeutic use; Interleukin-6/antagonists & inhibitors; Interleukin-6/biosynthesis; Pandemics; Pneumonia, Viral/complications; Pneumonia, Viral/drug therapy; Pneumonia, Viral/virology; Receptors, Interleukin-1/antagonists & inhibitors; Receptors, Interleukin-1/biosynthesis; SARS-CoV-2; Severe Acute Respiratory Syndrome/complications; Severe Acute Respiratory Syndrome/drug therapy; Severe Acute Respiratory Syndrome/virology; Severity of Illness Index; Vasculitis/complications; Vasculitis/drug therapy; Vasculitis/virology

Keywords

Complement; Covid-19; Immune complexes; Immunopathology; SARS-CoV2

Fulltext

XML

PubMed Links

Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Vasculitis / Immune Complex Diseases / Coronavirus Infections / Severe Acute Respiratory Syndrome / Betacoronavirus / Cytokine Release Syndrome / Antigen-Antibody Complex Type of study: Prognostic study Topics: Long Covid Language: English Journal: Clin Immunol Journal subject: Allergy and Immunology Year: 2020 Document Type: Article

Similar

MEDLINE

LILACS

LIS

Fulltext

XML

PubMed Links

Search on Google