P-selectin blockade in COVID-19-related ARDS.

Neri, Tommaso; Nieri, Dario; Celi, Alessandro

Neri, Tommaso; Nieri, Dario; Celi, Alessandro.

Neri T; Centro Dipartimentale di Biologia Cellulare Cardiorespiratoria, Dipartimento di Patologia Chirurgica, Medica, Molecolare e dell'Area Critica and Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
Nieri D; SC Pneumologia, Ospedale di Lucca, USL Toscana Nord-Ovest, Lucca, Italy.
Celi A; Centro Dipartimentale di Biologia Cellulare Cardiorespiratoria, Dipartimento di Patologia Chirurgica, Medica, Molecolare e dell'Area Critica and Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.

Am J Physiol Lung Cell Mol Physiol ; 318(6): L1237-L1238, 2020 06 01.

Article in English | MEDLINE | ID: covidwho-589959

Subject(s)

Coronavirus Infections/complications; P-Selectin/antagonists & inhibitors; P-Selectin/immunology; Pneumonia, Viral/complications; Respiratory Distress Syndrome/immunology; A549 Cells; Animals; Antibodies, Monoclonal, Humanized/therapeutic use; Betacoronavirus; COVID-19; Humans; Leukocyte Rolling; Membrane Glycoproteins; Mice, Knockout; Pandemics; Rats; Respiratory Distress Syndrome/drug therapy; Respiratory Distress Syndrome/etiology; SARS-CoV-2

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Respiratory Distress Syndrome / Coronavirus Infections / P-Selectin Topics: Long Covid Limits: Animals / Humans Language: English Journal: Am J Physiol Lung Cell Mol Physiol Journal subject: Molecular Biology / Physiology Year: 2020 Document Type: Article Affiliation country: Ajplung.00202.2020

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