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[Analysis of bronchoscope-guided tracheal intubation in 12 cases with coronavirus disease 2019 under the personal protective equipment with positive pressure protective hood].
Cai, S J; Wu, L L; Chen, D F; Li, Y X; Liu, Y J; Fan, Y Q; Du, S H; Huang, H; Liu, N; Cheng, L L; Deng, X L; Li, S Y.
  • Cai SJ; Intensive Care Unit, Guangzhou 8th People's Hospital, Guangzhou 440111, China.
  • Wu LL; Department of Pulmonary and Critical Care Medicine, the First Affiliated Hospital of Guangzhou Medical University, National Clinical Research Center for Respiratory, Guangzhou Institute of Respiratory Disease, Guangzhou 510120, China.
  • Chen DF; Department of Pulmonary and Critical Care Medicine, the First Affiliated Hospital of Guangzhou Medical University, National Clinical Research Center for Respiratory, Guangzhou Institute of Respiratory Disease, Guangzhou 510120, China.
  • Li YX; Intensive Care Unit, Guangzhou 8th People's Hospital, Guangzhou 440111, China.
  • Liu YJ; Intensive Care Unit, Guangzhou 8th People's Hospital, Guangzhou 440111, China.
  • Fan YQ; Intensive Care Unit, Guangzhou 8th People's Hospital, Guangzhou 440111, China.
  • Du SH; Intensive Care Unit, Guangzhou 8th People's Hospital, Guangzhou 440111, China.
  • Huang H; Intensive Care Unit, Guangzhou 8th People's Hospital, Guangzhou 440111, China.
  • Liu N; Intensive Care Unit, Guangzhou 8th People's Hospital, Guangzhou 440111, China.
  • Cheng LL; Department of Pulmonary and Critical Care Medicine, the First Affiliated Hospital of Guangzhou Medical University, National Clinical Research Center for Respiratory, Guangzhou Institute of Respiratory Disease, Guangzhou 510120, China.
  • Deng XL; Intensive Care Unit, Guangzhou 8th People's Hospital, Guangzhou 440111, China.
  • Li SY; Department of Pulmonary and Critical Care Medicine, the First Affiliated Hospital of Guangzhou Medical University, National Clinical Research Center for Respiratory, Guangzhou Institute of Respiratory Disease, Guangzhou 510120, China.
Zhonghua Jie He He Hu Xi Za Zhi ; 43(4): 332-334, 2020 Apr 12.
Article in Chinese | MEDLINE | ID: covidwho-591071
Semantic information from SemMedBD (by NLM)
1. Intubatio PREDISPOSES C0009450
Subject
Intubatio
Predicate
PREDISPOSES
Object
C0009450
2. intensive care unit LOCATION_OF Retrospective Studies
Subject
intensive care unit
Predicate
LOCATION_OF
Object
Retrospective Studies
3. Intubatio TREATS C5203670
Subject
Intubatio
Predicate
TREATS
Object
C5203670
4. Treatment Protocols USES Anesthetics
Subject
Treatment Protocols
Predicate
USES
Object
Anesthetics
5. fentanyl TREATS Sedated state
Subject
fentanyl
Predicate
TREATS
Object
Sedated state
6. morphine TREATS Sedated state
Subject
morphine
Predicate
TREATS
Object
Sedated state
7. Nucleic Acids PART_OF Virus
Subject
Nucleic Acids
Predicate
PART_OF
Object
Virus
8. Nucleic Acids NEG_PART_OF Health Personnel
Subject
Nucleic Acids
Predicate
NEG_PART_OF
Object
Health Personnel
9. Intubatio TREATS C0030705
Subject
Intubatio
Predicate
TREATS
Object
C0030705
10. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
11. Intubation, Intratracheal PREDISPOSES Communicable Diseases
Subject
Intubation, Intratracheal
Predicate
PREDISPOSES
Object
Communicable Diseases
12. intensive care unit LOCATION_OF Retrospective Studies
Subject
intensive care unit
Predicate
LOCATION_OF
Object
Retrospective Studies
13. Intubation, Intratracheal TREATS COVID-19
Subject
Intubation, Intratracheal
Predicate
TREATS
Object
COVID-19
14. Treatment Protocols USES Anesthetics
Subject
Treatment Protocols
Predicate
USES
Object
Anesthetics
15. fentanyl TREATS Sedated state
Subject
fentanyl
Predicate
TREATS
Object
Sedated state
16. morphine TREATS Sedated state
Subject
morphine
Predicate
TREATS
Object
Sedated state
17. Nucleic Acids PART_OF Virus
Subject
Nucleic Acids
Predicate
PART_OF
Object
Virus
18. Nucleic Acids NEG_PART_OF Health Personnel
Subject
Nucleic Acids
Predicate
NEG_PART_OF
Object
Health Personnel
19. Intubation, Intratracheal TREATS Patients
Subject
Intubation, Intratracheal
Predicate
TREATS
Object
Patients
20. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
ABSTRACT
Endotracheal intubation is an independent risk factor for respiratory infectious diseases. We conducted a retrospective study in 12 cases with COVID-19 who underwent endotracheal intubation at ICU of the Guangzhou eighth hospital from January 20 to February 10, 2020. The intubation procedure, anesthetic regimen, and complication were collected and analyzed. The 9 healthcare workers who involved in intubation received virus nucleic acid test and 14 days temperature monitoring. All 12 patients were successfully intubated under the guidance of bronchoscope, without any complications. Midazolam, Propofol and Morphine or fentanyl were used for sedation and analgesia, avoiding patients cough and agitated during the procedure. The 9 healthcare workers were protected under the Personal Protective Equipment(PPE) with positive pressure protective hood. The detection of oropharyngeal swab virus nucleic acid were negative in all 9 healthcare workers, none of them had fever or any respiratory symptoms. The PPE with positive pressure protective hood should be needed to perform bronchoscope-guided endotracheal intubation in patients with COVID-19, it could strengthen to protect healthcare workers from virus exposure.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Bronchoscopes / Personal Protective Equipment / Intubation, Intratracheal Type of study: Observational study / Risk factors Limits: Humans Country/Region as subject: Asia Language: Chinese Journal: Zhonghua Jie He He Hu Xi Za Zhi Year: 2020 Document Type: Article Affiliation country: Cma.j.cn112147-20200222-00153

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Bronchoscopes / Personal Protective Equipment / Intubation, Intratracheal Type of study: Observational study / Risk factors Limits: Humans Country/Region as subject: Asia Language: Chinese Journal: Zhonghua Jie He He Hu Xi Za Zhi Year: 2020 Document Type: Article Affiliation country: Cma.j.cn112147-20200222-00153