Clonal haematopoiesis and COVID-19: A possible deadly liaison.
Int J Immunogenet
; 47(4): 329-331, 2020 Aug.
Article
in English
| MEDLINE | ID: covidwho-591799
ABSTRACT
We provide evidence for a linear correlation between the frequency of clonal haematopoiesis and COVID-19 mortality rate. We discuss the mechanistic explanations for this association mediated by a pathological inflammatory response. Our hypothesis can be tested in COVID-19-infected patients and eventually lead to new approaches to risk stratification and therapy.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Aging
/
Coronavirus Infections
/
Clonal Selection, Antigen-Mediated
/
Hematopoiesis
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
Int J Immunogenet
Journal subject:
Allergy and Immunology
/
Genetics
Year:
2020
Document Type:
Article
Affiliation country:
Iji.12503
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