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Miller Fisher syndrome diagnosis and treatment in a patient with SARS-CoV-2.
Manganotti, Paolo; Pesavento, Valentina; Buoite Stella, Alex; Bonzi, Lucia; Campagnolo, Elena; Bellavita, Giulia; Fabris, Bruno; Luzzati, Roberto.
  • Manganotti P; Clinical Unit of Neurology, Department of Medicine, Surgery and Health Sciences, Cattinara University Hospital ASUGI, University of Trieste, Strada di Fiume, 447, 34149, Trieste, Italy. pmanganotti@units.it.
  • Pesavento V; Rehabilitation Unit, Cattinara University Hospital ASUGI, Via Giuseppe Lorenzo Gatteri, 25/1, 34125, Trieste, Italy.
  • Buoite Stella A; Clinical Unit of Neurology, Department of Medicine, Surgery and Health Sciences, Cattinara University Hospital ASUGI, University of Trieste, Strada di Fiume, 447, 34149, Trieste, Italy.
  • Bonzi L; Rehabilitation Unit, Cattinara University Hospital ASUGI, Via Giuseppe Lorenzo Gatteri, 25/1, 34125, Trieste, Italy.
  • Campagnolo E; Endocrinology Unit, Department of Medicine, Surgery and Health Sciences, Cattinara University Hospital ASUGI, University of Trieste, Strada di Fiume, 447, 34149, Trieste, Italy.
  • Bellavita G; Clinical Unit of Neurology, Department of Medicine, Surgery and Health Sciences, Cattinara University Hospital ASUGI, University of Trieste, Strada di Fiume, 447, 34149, Trieste, Italy.
  • Fabris B; Endocrinology Unit, Department of Medicine, Surgery and Health Sciences, Cattinara University Hospital ASUGI, University of Trieste, Strada di Fiume, 447, 34149, Trieste, Italy.
  • Luzzati R; Infectious Diseases Department, Department of Medicine, Surgery and Health Sciences, Cattinara University Hospital ASUGI, University of Trieste, Strada di Fiume, 447, 34149, Trieste, Italy.
J Neurovirol ; 26(4): 605-606, 2020 08.
Article in English | MEDLINE | ID: covidwho-593343
Semantic information from SemMedBD (by NLM)
1. 2019 novel coronavirus PROCESS_OF Patients
Subject
2019 novel coronavirus
Predicate
PROCESS_OF
Object
Patients
2. Pneumonia PROCESS_OF Woman
Subject
Pneumonia
Predicate
PROCESS_OF
Object
Woman
3. Neurologic Examination DIAGNOSES Miller Fisher Syndrome
Subject
Neurologic Examination
Predicate
DIAGNOSES
Object
Miller Fisher Syndrome
4. Lower Extremity LOCATION_OF Signs and Symptom
Subject
Lower Extremity
Predicate
LOCATION_OF
Object
Signs and Symptom
5. Lower Extremity LOCATION_OF Hyporeflexia
Subject
Lower Extremity
Predicate
LOCATION_OF
Object
Hyporeflexia
6. 2019 novel coronavirus PROCESS_OF Patients
Subject
2019 novel coronavirus
Predicate
PROCESS_OF
Object
Patients
7. Pneumonia PROCESS_OF Woman
Subject
Pneumonia
Predicate
PROCESS_OF
Object
Woman
8. Neurologic Examination DIAGNOSES Miller Fisher Syndrome
Subject
Neurologic Examination
Predicate
DIAGNOSES
Object
Miller Fisher Syndrome
9. Lower Extremity LOCATION_OF Signs and Symptoms, Respiratory
Subject
Lower Extremity
Predicate
LOCATION_OF
Object
Signs and Symptoms, Respiratory
10. Lower Extremity LOCATION_OF Hyporeflexia
Subject
Lower Extremity
Predicate
LOCATION_OF
Object
Hyporeflexia
ABSTRACT
This case report describes the clinical characteristics of a 50-year-old woman that developed SARS-CoV-2 pneumonia and was admitted at the COVID-19 dedicated unit where she developed neurological symptoms 10 days after admission. After neurological examination, including a panel of blood cerebrospinal fluid biomarkers, a diagnosis of Miller Fisher syndrome (MFS) was hypothesized and intravenous immunoglobulin therapy (IVIG) was initiated. Fourteen days after the start of IVIG treatment, the patient has been discharged at home with the resolution of respiratory symptoms and only minor hyporeflexia at the lower limbs, without any side effect.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Immunoglobulins, Intravenous / Coronavirus Infections / Miller Fisher Syndrome Type of study: Diagnostic study Limits: Female / Humans / Middle aged Language: English Journal: J Neurovirol Journal subject: Neurology / Virology Year: 2020 Document Type: Article Affiliation country: S13365-020-00858-9

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Immunoglobulins, Intravenous / Coronavirus Infections / Miller Fisher Syndrome Type of study: Diagnostic study Limits: Female / Humans / Middle aged Language: English Journal: J Neurovirol Journal subject: Neurology / Virology Year: 2020 Document Type: Article Affiliation country: S13365-020-00858-9