Secondary HLH is uncommon in severe COVID-19.

Wood, Henry; Jones, John R; Hui, Kit; Mare, Tracey; Pirani, Tasneem; Galloway, James; Metaxa, Victoria; Benjamin, Reuben; Rutherford, Andrew; Cain, Sharon; Kulasekararaj, Austin G

Wood, Henry; Jones, John R; Hui, Kit; Mare, Tracey; Pirani, Tasneem; Galloway, James; Metaxa, Victoria; Benjamin, Reuben; Rutherford, Andrew; Cain, Sharon; Kulasekararaj, Austin G.

Wood H; Department of Haematological Medicine, King's College Hospital NHS Foundation Trust, London, UK.
Jones JR; King's College London, London, UK.
Hui K; Department of Haematological Medicine, King's College Hospital NHS Foundation Trust, London, UK.
Mare T; Viapath, King's College Hospital NHS Foundation Trust, London, UK.
Pirani T; Viapath, King's College Hospital NHS Foundation Trust, London, UK.
Galloway J; Department of Critical Care, King's College Hospital NHS Foundation Trust, London, UK.
Metaxa V; King's College London, London, UK.
Benjamin R; Department of Rheumatology, King's College Hospital NHS Foundation Trust, London, UK.
Rutherford A; Department of Critical Care, King's College Hospital NHS Foundation Trust, London, UK.
Cain S; Department of Haematological Medicine, King's College Hospital NHS Foundation Trust, London, UK.
Kulasekararaj AG; King's College London, London, UK.

Br J Haematol ; 190(5): e283-e285, 2020 09.

Article in English | MEDLINE | ID: covidwho-593576

Subject(s)

Betacoronavirus/metabolism; Coronavirus Infections; Pandemics; Pneumonia, Viral; Adult; Aged; Aged, 80 and over; COVID-19; Coronavirus Infections/blood; Coronavirus Infections/complications; Coronavirus Infections/epidemiology; Coronavirus Infections/therapy; Cross-Sectional Studies; Female; Humans; Lymphohistiocytosis, Hemophagocytic/blood; Lymphohistiocytosis, Hemophagocytic/epidemiology; Lymphohistiocytosis, Hemophagocytic/etiology; Lymphohistiocytosis, Hemophagocytic/therapy; Male; Middle Aged; Pneumonia, Viral/blood; Pneumonia, Viral/complications; Pneumonia, Viral/epidemiology; Pneumonia, Viral/therapy; SARS-CoV-2; Severity of Illness Index

Keywords

COVID-19; HLH; SARS-CoV-2; cytokine; leucoerythroblastic; secondary haemophagocytic lymphohistiocytosis

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Pandemics / Betacoronavirus Type of study: Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: English Journal: Br J Haematol Year: 2020 Document Type: Article Affiliation country: Bjh.16934

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