Happy Hypoxemia in COVID-19-A Neural Hypothesis.

U R, Anoop; Verma, Kavita

U R, Anoop; Verma, Kavita.

U R A; UR Anoop Research Group, Pondicherry, India 605008.
Verma K; UR Anoop Research Group, Pondicherry, India 605008.

ACS Chem Neurosci ; 11(13): 1865-1867, 2020 07 01.

Article in English | MEDLINE | ID: covidwho-595686

ABSTRACT

ABSTRACT

Many COVID-19 patients are presenting with atypical clinical features. Happy hypoxemia with almost normal breathing, anosmia in the absence of rhinitis or nasal obstruction, and ageusia are some of the reported atypical clinical findings. Based on the clinical manifestations of the disease, we are proposing a new hypothesis that SARS-CoV-2 mediated inflammation of the nucleus tractus solitarius may be the reason for happy hypoxemia in COVID-19 patients.

Subject(s)

Betacoronavirus; Coronavirus Infections/physiopathology; Hypoxia/physiopathology; Pneumonia, Viral/physiopathology; Solitary Nucleus/physiopathology; Solitary Nucleus/virology; COVID-19; Coronavirus Infections/complications; Cranial Nerves/physiopathology; Cranial Nerves/virology; Humans; Hypoxia/etiology; Inflammation/etiology; Inflammation/physiopathology; Inflammation/virology; Pandemics; Pneumonia, Viral/complications; SARS-CoV-2

Keywords

Ageusia; COVID-19; Carotid body; Cranial nerves; Happy hypoxemia; Nucleus tractus solitarius

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Solitary Nucleus / Coronavirus Infections / Betacoronavirus / Hypoxia Type of study: Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: ACS Chem Neurosci Year: 2020 Document Type: Article

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