Molecular structure analyses suggest strategies to therapeutically target SARS-CoV-2.

Zhang, Yi; Kutateladze, Tatiana G

Zhang, Yi; Kutateladze, Tatiana G.

Zhang Y; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO, 80045, USA.
Kutateladze TG; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO, 80045, USA. tatiana.kutateladze@cuanschutz.edu.

Nat Commun ; 11(1): 2920, 2020 06 10.

Article in English | MEDLINE | ID: covidwho-596339

Subject(s)

Antiviral Agents/chemistry; Betacoronavirus/chemistry; Coronavirus Infections/therapy; Coronavirus Infections/virology; Pneumonia, Viral/therapy; Pneumonia, Viral/virology; Spike Glycoprotein, Coronavirus/chemistry; Viral Vaccines/chemistry; Angiotensin-Converting Enzyme 2; Antiviral Agents/therapeutic use; Betacoronavirus/drug effects; Betacoronavirus/immunology; Betacoronavirus/metabolism; COVID-19; COVID-19 Vaccines; Coronavirus 3C Proteases; Coronavirus Infections/drug therapy; Coronavirus Infections/prevention & control; Cysteine Endopeptidases/chemistry; Cysteine Endopeptidases/metabolism; Humans; Models, Molecular; Pandemics/prevention & control; Peptidyl-Dipeptidase A/chemistry; Peptidyl-Dipeptidase A/metabolism; Pneumonia, Viral/drug therapy; Pneumonia, Viral/prevention & control; SARS-CoV-2; Spike Glycoprotein, Coronavirus/immunology; Viral Nonstructural Proteins/chemistry; Viral Nonstructural Proteins/metabolism; Viral Vaccines/therapeutic use

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Pneumonia, Viral / Viral Vaccines / Coronavirus Infections / Spike Glycoprotein, Coronavirus / Betacoronavirus Topics: Vaccines Limits: Humans Language: English Journal: Nat Commun Journal subject: Biology / Science Year: 2020 Document Type: Article Affiliation country: S41467-020-16779-4

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