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Cerebrovascular events in COVID-19 patients.
Mishra, Ajay Kumar; Sahu, Kamal Kant; George, Anu Anna; Sargent, Jennifer; Lal, Amos.
  • Mishra AK; Department of Internal Medicine, St. Vincent Hospital, Worcester, MA. Ajay.Mishra@stvincenthosptial.com.
  • Sahu KK; Department of Internal Medicine, St. Vincent Hospital, Worcester, MA. Kamalkant.Sahu@stvincenthospital.com.
  • George AA; Department of Internal Medicine, St. Vincent Hospital, Worcester, MA. anugeorg@gmail.com.
  • Sargent J; Department of Internal Medicine, St. Vincent Hospital, Worcester; University of Massachusetts Medical School, Worcester, MA. Jennifer.Sargent@stvincenthospital.com.
  • Lal A; Department of Internal Medicine, Division of Pulmonology and Critical Care Medicine, Mayo Clinic, Rochester, MN. manavamos@gmail.com.
Monaldi Arch Chest Dis ; 90(2)2020 Jun 10.
Article in English | MEDLINE | ID: covidwho-596934
ABSTRACT
Neurological manifestations in patients with COVID-19 are more frequently being reported. Cerebrovascular events have been reported in around 3% of patients. In this review we summarize the published literature on cerebrovascular events in patients with COVID-19 as available on the PubMed database. So far, 3 studies have reported cerebrovascular events. Cerebrovascular events were identified on screening patients with decreased consciousness or in the presence of focal neurological deficits. These events were common in elderly, critically ill patients and in patients with prior cardio-cerebrovascular comorbidities. The diagnosis of cerebrovascular events was confirmed with computed tomography of the brain in most studies reporting neurological events. Multiple pathological mechanisms have been postulated regarding the process of neurological and vascular injury among which cytokine storm is shown to correlate with mortality. Patients with severe illness are found to have a higher cardio- cerebrovascular comorbidity. With an increasing number of cases and future prospective studies, the exact mechanism by which these cerebrovascular events occur and attribute to the poor outcome will be better understood.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Cerebrovascular Disorders / Critical Illness / Coronavirus Infections / Betacoronavirus Type of study: Cohort study / Diagnostic study / Observational study / Prognostic study / Reviews Topics: Long Covid Limits: Humans Language: English Year: 2020 Document Type: Article Affiliation country: Monaldi.2020.1341

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Cerebrovascular Disorders / Critical Illness / Coronavirus Infections / Betacoronavirus Type of study: Cohort study / Diagnostic study / Observational study / Prognostic study / Reviews Topics: Long Covid Limits: Humans Language: English Year: 2020 Document Type: Article Affiliation country: Monaldi.2020.1341