Impaired cardiac function is associated with mortality in patients with acute COVID-19 infection.
Clin Res Cardiol
; 109(12): 1491-1499, 2020 Dec.
Article
in English
| MEDLINE | ID: covidwho-597440
ABSTRACT
BACKGROUND:
COVID-19 infection may cause severe respiratory distress and is associated with increased morbidity and mortality. Impaired cardiac function and/or pre-existing cardiovascular disease may be associated with poor prognosis. In the present study, we report a comprehensive cardiovascular characterization in the first consecutive collective of patients that was admitted and treated at the University Hospital of Tübingen, Germany.METHODS:
123 consecutive patients with COVID-19 were included. Routine blood sampling, transthoracic echocardiography and electrocardiography were performed at hospital admission.RESULTS:
We found that impaired left-ventricular and right-ventricular function as well as tricuspid regurgitation > grade 1 were significantly associated with higher mortality. Furthermore, elevated levels of myocardial distress markers (troponin-I and NT pro-BNP) were associated with poor prognosis in this patient collective.CONCLUSION:
Impaired cardiac function is associated with poor prognosis in COVID-19 positive patients. Consequently, treatment of these patients should include careful guideline-conform cardiovascular evaluation and treatment. Thus, formation of a competent Cardio-COVID-19 team may represent a major clinical measure to optimize therapy of cardiovascular patients during this pandemic.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Tricuspid Valve Insufficiency
/
Ventricular Function, Left
/
Ventricular Function, Right
/
Ventricular Dysfunction, Right
/
Ventricular Dysfunction, Left
/
COVID-19
Type of study:
Cohort study
/
Diagnostic study
/
Experimental Studies
/
Observational study
/
Prognostic study
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Europa
Language:
English
Journal:
Clin Res Cardiol
Journal subject:
Cardiology
Year:
2020
Document Type:
Article
Affiliation country:
S00392-020-01683-0
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