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Transmission Potential of Asymptomatic and Paucisymptomatic Severe Acute Respiratory Syndrome Coronavirus 2 Infections: A 3-Family Cluster Study in China.
Jiang, Xiao-Lin; Zhang, Xiao-Li; Zhao, Xiang-Na; Li, Cun-Bao; Lei, Jie; Kou, Zeng-Qiang; Sun, Wen-Kui; Hang, Yang; Gao, Feng; Ji, Sheng-Xiang; Lin, Can-Fang; Pang, Bo; Yao, Ming-Xiao; Anderson, Benjamin D; Wang, Guo-Lin; Yao, Lin; Duan, Li-Jun; Kang, Dian-Min; Ma, Mai-Juan.
  • Jiang XL; Shandong Provincial Center for Disease Control and Prevention, Jinan, China.
  • Zhang XL; Linyi Center for Disease Control and Prevention, Linyi, China.
  • Zhao XN; Institute of Disease Control and Prevention, Chinese People's Liberation Army, Beijing, China.
  • Li CB; Lanshan District Center for Disease Control and Prevention, Linyi, China.
  • Lei J; Shandong Provincial Center for Disease Control and Prevention, Jinan, China.
  • Kou ZQ; Shandong Provincial Center for Disease Control and Prevention, Jinan, China.
  • Sun WK; Shandong Provincial Center for Disease Control and Prevention, Jinan, China.
  • Hang Y; Shandong Provincial Center for Disease Control and Prevention, Jinan, China.
  • Gao F; Linyi People's Hospital, Linyi, China.
  • Ji SX; Linyi Center for Disease Control and Prevention, Linyi, China.
  • Lin CF; Lanshan District Center for Disease Control and Prevention, Linyi, China.
  • Pang B; Shandong Provincial Center for Disease Control and Prevention, Jinan, China.
  • Yao MX; Shandong Provincial Center for Disease Control and Prevention, Jinan, China.
  • Anderson BD; Global Health Research Center, Duke Kunshan University, Kunshan, Jiangsu, China.
  • Wang GL; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
  • Yao L; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
  • Duan LJ; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
  • Kang DM; Shandong Provincial Center for Disease Control and Prevention, Jinan, China.
  • Ma MJ; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
J Infect Dis ; 221(12): 1948-1952, 2020 06 11.
Article in English | MEDLINE | ID: covidwho-599716
ABSTRACT
Data concerning the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in asymptomatic and paucisymptomatic patients are lacking. We report a 3-family cluster of infections involving asymptomatic and paucisymptomatic transmission. Eight of 15 (53%) members from 3 families were confirmed with SARS-CoV-2 infection. Of 8 patients, 3 were asymptomatic and 1 was paucisymptomatic. An asymptomatic mother transmitted the virus to her son, and a paucisymptomatic father transmitted the virus to his 3-month-old daughter. SARS-CoV-2 was detected in the environment of 1 household. The complete genomes of SARS-CoV-2 from the patients were > 99.9% identical and were clustered with other SARS-CoV-2 sequences reported from China and other countries.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Asymptomatic Infections Type of study: Diagnostic study / Observational study / Randomized controlled trials Limits: Adult / Aged / Female / Humans / Infant / Male / Middle aged Country/Region as subject: Asia Language: English Journal: J Infect Dis Year: 2020 Document Type: Article Affiliation country: Infdis

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Asymptomatic Infections Type of study: Diagnostic study / Observational study / Randomized controlled trials Limits: Adult / Aged / Female / Humans / Infant / Male / Middle aged Country/Region as subject: Asia Language: English Journal: J Infect Dis Year: 2020 Document Type: Article Affiliation country: Infdis