Revisiting the Protein C Pathway: An Opportunity for Adjunctive Intervention in COVID-19?

Mazzeffi, Michael; Chow, Jonathan H; Amoroso, Anthony; Tanaka, Kenichi

Mazzeffi, Michael; Chow, Jonathan H; Amoroso, Anthony; Tanaka, Kenichi.

Mazzeffi M; From the Department of Anesthesiology.
Chow JH; From the Department of Anesthesiology.
Amoroso A; Division of Infectious Disease, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland.
Tanaka K; From the Department of Anesthesiology.

Anesth Analg ; 131(3): 690-693, 2020 09.

Article in English | MEDLINE | ID: covidwho-601052

Subject(s)

Betacoronavirus; Blood Coagulation Disorders/blood; Blood Coagulation Disorders/drug therapy; Coronavirus Infections/blood; Coronavirus Infections/drug therapy; Pneumonia, Viral/blood; Pneumonia, Viral/drug therapy; Protein C/administration & dosage; Anti-Inflammatory Agents/administration & dosage; Anti-Inflammatory Agents/blood; Anticoagulants/administration & dosage; Anticoagulants/blood; Blood Coagulation Disorders/epidemiology; Blood Coagulation Factors/administration & dosage; COVID-19; Chemotherapy, Adjuvant/methods; Coronavirus Infections/epidemiology; Humans; Pandemics; Pneumonia, Viral/epidemiology; Protein C/metabolism; Receptors, Cell Surface/administration & dosage; Receptors, Cell Surface/blood; Recombinant Proteins/administration & dosage; Recombinant Proteins/blood; SARS-CoV-2; Thrombomodulin/administration & dosage; Thrombomodulin/blood

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Blood Coagulation Disorders / Protein C / Coronavirus Infections / Betacoronavirus Type of study: Experimental Studies / Observational study Limits: Humans Language: English Journal: Anesth Analg Year: 2020 Document Type: Article

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