Infant With SARS-CoV-2 Infection Causing Severe Lung Disease Treated With Remdesivir.
Pediatrics
; 146(3)2020 09.
Article
in English
| MEDLINE | ID: covidwho-607311
ABSTRACT
We describe an ex-premature infant presenting with severe acute respiratory syndrome coronavirus 2 infection in the fifth week of life. In current reports, researchers indicate that acute symptomatic severe acute respiratory syndrome coronavirus 2 infection is relatively rare and much less severe than in adults. This case highlights that infection can be associated with life-threatening pulmonary disease in young infants and that infection can follow a similar disease course to that described in adults. We provide first data on the use of the novel antiviral remdesivir in a young child and an innovative approach to expedited approval from a multidisciplinary clinical team and bioethics committee for compassionate access to the drug.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Antiviral Agents
/
Pneumonia, Viral
/
Infant, Premature
/
Adenosine Monophosphate
/
Coronavirus Infections
/
Severe Acute Respiratory Syndrome
/
Alanine
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Female
/
Humans
/
Infant
Language:
English
Year:
2020
Document Type:
Article
Affiliation country:
Peds.2020-1701
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