The renin-angiotensin system: An integrated view of lung disease and coagulopathy in COVID-19 and therapeutic implications.
J Exp Med
; 217(8)2020 08 03.
Article
in English
| MEDLINE | ID: covidwho-607919
ABSTRACT
The renin-angiotensin system (RAS) has long been appreciated as a major regulator of blood pressure, but has more recently been recognized as a mechanism for modulating inflammation as well. While there has been concern in COVID-19 patients over the use of drugs that target this system, the RAS has not been explored fully as a druggable target. The abbreviated description of the RAS suggests that its dysregulation may be at the center of COVID-19.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Coronavirus Infections
/
Lung
/
Lung Diseases
Type of study:
Prognostic study
Limits:
Animals
/
Humans
Language:
English
Year:
2020
Document Type:
Article
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