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Overview of therapeutic drug research for COVID-19 in China.
Li, Heng; Yang, Li; Liu, Fei-Fei; Ma, Xin-Na; He, Pei-Lan; Tang, Wei; Tong, Xian-Kun; Zuo, Jian-Ping.
  • Li H; Laboratory of Immunopharmacology, Shanghai Institute of MateriaMedica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Yang L; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Liu FF; Laboratory of Immunopharmacology, Shanghai Institute of MateriaMedica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Ma XN; Laboratory of Immunopharmacology, Shanghai Institute of MateriaMedica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • He PL; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Tang W; Laboratory of Immunology and Virology, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
  • Tong XK; Laboratory of Immunopharmacology, Shanghai Institute of MateriaMedica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Zuo JP; Laboratory of Immunopharmacology, Shanghai Institute of MateriaMedica, Chinese Academy of Sciences, Shanghai, 201203, China.
Acta Pharmacol Sin ; 41(9): 1133-1140, 2020 Sep.
Article in English | MEDLINE | ID: covidwho-608476
ABSTRACT
Since the outbreak of novel coronavirus pneumonia (COVID-19) in December 2019, more than 2,500,000 people worldwide have been diagnosed with SARS-CoV-2 as of April 22. In response to this epidemic, China has issued seven trial versions of diagnosis and treatment protocol for COVID-19. According to the information that we have collected so far, this article provides an overview of potential therapeutic drugs and compounds with much attention, including favipiravir and hydroxychloroquine, as well as traditional Chinese medicine, which have been reported with good clinical treatment effects. Moreover, with further understanding of SARS-CoV-2 virus, new drugs targeting specific SARS-CoV-2 viral components arise and investigations on these novel anti-SARS-CoV-2 agents are also reviewed.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Pneumonia, Viral / Coronavirus Infections / Pandemics / Betacoronavirus / Medicine, Chinese Traditional Type of study: Prognostic study / Randomized controlled trials Topics: Traditional medicine Limits: Humans Language: English Journal: Acta Pharmacol Sin Journal subject: Pharmacology Year: 2020 Document Type: Article Affiliation country: S41401-020-0438-y

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Pneumonia, Viral / Coronavirus Infections / Pandemics / Betacoronavirus / Medicine, Chinese Traditional Type of study: Prognostic study / Randomized controlled trials Topics: Traditional medicine Limits: Humans Language: English Journal: Acta Pharmacol Sin Journal subject: Pharmacology Year: 2020 Document Type: Article Affiliation country: S41401-020-0438-y