SARS-CoV-2: diagnostic and design conundrums in the context of male factor infertility.
Reprod Biomed Online
; 41(3): 365-369, 2020 09.
Article
in English
| MEDLINE | ID: covidwho-610971
ABSTRACT
The question of whether SARS-CoV-2 (severe acute respiratory syndrome-related coronavirus-2 [SARS-CoV-2], leading to the COVID-19 infection) can be harboured in the testes and/or semen is currently unanswered. It is essential to understand the limitations of both antibody and real-time PCR tests in interpreting SARS-CoV-2 data in relation to analyses of semen and testicular tissue without appropriate controls. This article critically analyses the evidence so far on this, and the possible implications. The limitations of diagnostic tests in both sampling and testing methodologies, their validation and their relevance in interpreting data are also highlighted.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Testis
/
Coronavirus Infections
/
Clinical Laboratory Techniques
/
Betacoronavirus
/
Infertility, Male
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Humans
/
Male
Language:
English
Journal:
Reprod Biomed Online
Journal subject:
Reproductive Medicine
Year:
2020
Document Type:
Article
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