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Vaccines for COVID-19: The current state of play.
Koirala, Archana; Joo, Ye Jin; Khatami, Ameneh; Chiu, Clayton; Britton, Philip N.
  • Koirala A; National Centre for Immunisation Research and Surveillance, Westmead, NSW, Australia; Department of Infectious Diseases, Nepean Hospital, Penrith, NSW, Australia. Electronic address: Archana.Koirala@health.nsw.gov.au.
  • Joo YJ; National Centre for Immunisation Research and Surveillance, Westmead, NSW, Australia. Electronic address: YeJin.Joo@health.nsw.gov.au.
  • Khatami A; Sydney Medical School, The University of Sydney, NSW, Australia; Department of Infectious Diseases and Microbiology, The Children's Hospital at Westmead, NSW, Australia. Electronic address: ameneh.khatami@health.nsw.gov.au.
  • Chiu C; National Centre for Immunisation Research and Surveillance, Westmead, NSW, Australia; Sydney Medical School, The University of Sydney, NSW, Australia. Electronic address: clayton.chiu@health.nsw.gov.au.
  • Britton PN; Sydney Medical School, The University of Sydney, NSW, Australia; Department of Infectious Diseases and Microbiology, The Children's Hospital at Westmead, NSW, Australia. Electronic address: philip.britton@health.nsw.gov.au.
Paediatr Respir Rev ; 35: 43-49, 2020 Sep.
Article in English | MEDLINE | ID: covidwho-611163
ABSTRACT
There is a strong consensus globally that a COVID-19 vaccine is likely the most effective approach to sustainably controlling the COVID-19 pandemic. An unprecedented research effort and global coordination has resulted in a rapid development of vaccine candidates and initiation of trials. Here, we review vaccine types, and progress with 10 vaccine candidates against SARS-CoV-2 - the virus that causes COVID-19 - currently undergoing early phase human trials. We also consider the many challenges of developing and deploying a new vaccine on a global scale, and recommend caution with respect to our expectations of the timeline that may be ahead.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Viral Vaccines / Vaccines, Synthetic / Coronavirus Infections / Vaccines, DNA / Pandemics / Betacoronavirus Type of study: Prognostic study / Randomized controlled trials Topics: Vaccines Limits: Humans Language: English Journal: Paediatr Respir Rev Journal subject: Pediatrics Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Viral Vaccines / Vaccines, Synthetic / Coronavirus Infections / Vaccines, DNA / Pandemics / Betacoronavirus Type of study: Prognostic study / Randomized controlled trials Topics: Vaccines Limits: Humans Language: English Journal: Paediatr Respir Rev Journal subject: Pediatrics Year: 2020 Document Type: Article