A Case of Covid-19 Patient with Acute Limb Ischemia and Heparin Resistance.
Ann Vasc Surg
; 68: 88-92, 2020 Oct.
Article
in English
| MEDLINE | ID: covidwho-612189
ABSTRACT
Heparin resistance is an uncommon phenomenon defined as the need for high-dose unfractionated heparin (UFH) of more than 35,000 IU/day to achieve the target activated partial-thromboplastin time ratio or the failure to achieve the desired activated clotting time after a full UFH dose. This rare phenomenon is being more commonly observed in Covid-19 patients in a hypercoagulable state. We describe a Covid-19 patient confirmed by reverse-transcriptase polymerase chain reaction assay, with acute limb ischemia, who developed heparin resistance. The patient was managed by the departments of vascular surgery, anesthesia and intensive care, and the Coagulation Service and Thrombosis Research from San Raffaele Scientific Institute, Milan, Italy.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Drug Resistance
/
Heparin
/
Coronavirus Infections
/
Lower Extremity
/
Betacoronavirus
/
Ischemia
Type of study:
Case report
/
Diagnostic study
/
Observational study
Topics:
Long Covid
Limits:
Aged
/
Humans
/
Male
Language:
English
Journal:
Ann Vasc Surg
Journal subject:
Vascular Diseases
Year:
2020
Document Type:
Article
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