Severe immune thrombocytopenic purpura in critical COVID-19.
Int J Hematol
; 112(5): 746-750, 2020 Nov.
Article
in English
| MEDLINE | ID: covidwho-619933
ABSTRACT
COVID-19 is a new disease with many undescribed clinical manifestations. We report herein a case of severe immune thrombocytopenic purpura (ITP) in a critical COVID-19 patient. A patient presented a severe episode of immune thrombocytopenia (< 10 × 109/L) 20 days after admission for a critical COVID-19. This thrombocytopenia was associated with a life-threatening bleeding. Response to first-line therapies was delayed as it took up to 13 days after initiation of intravenous immunoglobulin and high-dose dexamethasone to observe an increase in platelet count. COVID-19 may be associated with late presenting severe ITP. Such ITP may also be relatively resistant to first-line agents. Hematological manifestations of COVID-19, such as the ones associated with life-threatening bleeding, must be recognized.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Purpura, Thrombocytopenic, Idiopathic
/
Coronavirus Infections
/
Pandemics
Type of study:
Case report
/
Prognostic study
Topics:
Long Covid
Limits:
Humans
/
Male
/
Middle aged
Language:
English
Journal:
Int J Hematol
Journal subject:
Hematology
Year:
2020
Document Type:
Article
Affiliation country:
S12185-020-02931-9
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