A Comprehensive Analysis of Clinical Trials in the COVID-19 Pandemic Era.
Medicina (Kaunas)
; 56(6)2020 Jun 26.
Article
in English
| MEDLINE | ID: covidwho-622723
ABSTRACT
Background and objective:
Despite medical advances, we are facing the unprecedented disaster of the coronavirus disease 2019 (COVID-19) pandemic without available treatments and effective vaccines. As the COVID-19 pandemic has approached its culmination, desperate efforts have been made to seek proper treatments and response strategies, and the number of clinical trials has been rapidly increasing. In this time of the pandemic, it is believed that learning lessons from it would be meaningful in preparing for future pandemics. Thus, this study aims at providing a comprehensive landscape of COVID-19 related clinical trials based on the ClinicalTrials.gov database. Materials andmethods:
Up to 30 March 2020, we identified a total of 147 eligible clinical trials and reviewed the overview of the studies.Results:
Until then, the most clinical trials were set up in China. Treatment approaches are the most frequent purpose of the registered studies. Chloroquine, interferon, and antiviral agents such as remdesivir, lopinavir, and ritonavir are agents under investigation in these trials.Conclusions:
In this study, we introduced the promising therapeutic options that many researchers and clinicians are interested in, and to address the hidden issues behind clinical trials in this COVID-19 pandemic.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Clinical Trials as Topic
/
Coronavirus Infections
Type of study:
Prognostic study
/
Randomized controlled trials
Topics:
Vaccines
Limits:
Humans
Language:
English
Journal subject:
Medicine
Year:
2020
Document Type:
Article
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