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Longitudinal anti-SARS-CoV-2 antibody profile and neutralization activity of a COVID-19 patient.
Yin, Shengxia; Tong, Xin; Huang, Aijun; Shen, Han; Li, Yang; Liu, Yong; Wu, Chao; Huang, Rui; Chen, Yuxin.
  • Yin S; Department of Infectious Diseases, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, Jiangsu, China.
  • Tong X; Department of Infectious Diseases, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, Jiangsu, China.
  • Huang A; Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, Jiangsu, China.
  • Shen H; Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, Jiangsu, China.
  • Li Y; Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, Jiangsu, China.
  • Liu Y; Department of Experimental Medicine, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, Jiangsu, China.
  • Wu C; Department of Infectious Diseases, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, Jiangsu, China.
  • Huang R; Department of Infectious Diseases, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, Jiangsu, China. Electronic address: doctor_hr@126.com.
  • Chen Y; Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, Jiangsu, China. Electronic address: yuxin_chen2015@163.com.
J Infect ; 81(3): e31-e32, 2020 Sep.
Article in English | MEDLINE | ID: covidwho-625901
ABSTRACT
We followed-up a mild COVID-19 patient for 91 days and serially monitored his serum antibodies to four SARS-CoV-2 related antigens (NP, RBD, S1 and ECD) and neutralization activities. Our data revealed a profile of serial antibody responses during the progress and a quick decline of neutralization activities after discharge.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Antibodies, Neutralizing / Betacoronavirus / Antibodies, Viral Type of study: Case report / Cohort study / Observational study / Prognostic study Limits: Adult / Humans / Male Language: English Journal: J Infect Year: 2020 Document Type: Article Affiliation country: J.jinf.2020.06.076

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Antibodies, Neutralizing / Betacoronavirus / Antibodies, Viral Type of study: Case report / Cohort study / Observational study / Prognostic study Limits: Adult / Humans / Male Language: English Journal: J Infect Year: 2020 Document Type: Article Affiliation country: J.jinf.2020.06.076