Making Sense of Mutation: What D614G Means for the COVID-19 Pandemic Remains Unclear.

Grubaugh, Nathan D; Hanage, William P; Rasmussen, Angela L

Grubaugh, Nathan D; Hanage, William P; Rasmussen, Angela L.

Grubaugh ND; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT 06510, USA. Electronic address: grubaughlab@gmail.com.
Hanage WP; Center for Communicable Disease Dynamics, Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.
Rasmussen AL; Center for Infection and Immunity, Columbia Mailman School of Public Health, New York, NY 10032, USA.

Cell ; 182(4): 794-795, 2020 08 20.

Article in English | MEDLINE | ID: covidwho-625969

ABSTRACT

ABSTRACT

In this issue of Cell, Korber et al. found that a SARS-CoV-2 variant in the spike protein D614G rapidly became dominant around the world. Although clinical and in vitro data suggest that D614G changes the virus phenotype, the impact of the mutation on transmission, disease, and vaccine and therapeutic development are largely unknown.

Subject(s)

Betacoronavirus; Coronavirus Infections; Pandemics; Pneumonia, Viral; COVID-19; Humans; Mutation; SARS-CoV-2

Fulltext

XML

PubMed Links

Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Pandemics / Betacoronavirus Type of study: Prognostic study Topics: Vaccines / Variants Limits: Humans Language: English Journal: Cell Year: 2020 Document Type: Article

Similar

MEDLINE

LILACS

LIS

Fulltext

XML

PubMed Links

Search on Google