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National sero-surveillance to monitor the trend of SARS-CoV-2 infection transmission in India: Protocol for community-based surveillance.
Kumar, Muthusamy Santhosh; Bhatnagar, Tarun; Manickam, Ponnaiah; Kumar, V Saravana; Rade, Kiran; Shah, Naman; Kant, Shashi; Babu, Giridhara R; Zodpey, Sanjay; Girish Kumar, C P; Vivian Thangaraj, Jeromie Wesley; Chatterjee, Pranab; Kanungo, Suman; Pandey, Ravindra Mohan; Murhekar, Manoj; Singh, Sujeet K; Sarkar, Swarup; Muliyi, J P; Gangakhedkar, Raman R; Reddy, D C S.
  • Kumar MS; ICMR School of Public Health, Chennai, India.
  • Bhatnagar T; ICMR School of Public Health, Chennai, India.
  • Manickam P; ICMR-National Institute of Epidemiology, Chennai, India.
  • Kumar VS; Division of Epidemiology & Bio-Statistics, Chennai, India.
  • Rade K; WHO Country Office for India, New Delhi, India.
  • Shah N; Jan Swasthya Sahyog, Bilaspur, Chhattisgarh, India.
  • Kant S; Centre for Community Medicine, Bengaluru, India.
  • Babu GR; Indian Institute of Public Health-Bengaluru, India.
  • Zodpey S; Indian Institute of Public Health-Delhi, Public Health Foundation of India, New Delhi, India.
  • Girish Kumar CP; ICMR-National Institute of Epidemiology, Chennai, India.
  • Vivian Thangaraj JW; ICMR-National Institute of Epidemiology, Chennai, India.
  • Chatterjee P; Translational Global Health Policy Research Cell (Department of Health Research), Indian Council of Medical Research, New Delhi, India.
  • Kanungo S; ICMR-National Institute of Cholera & Enteric Diseases, Kolkata, West Bengal, India.
  • Pandey RM; Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India.
  • Murhekar M; ICMR-National Institute of Epidemiology, Chennai, India.
  • Singh SK; National Centre for Disease Control, Delhi, India.
  • Sarkar S; Translational Global Health Policy Research Cell (Department of Health Research), Indian Council of Medical Research, New Delhi, India.
  • Muliyi JP; Independent Consultant, Vellore, Tamil Nadu, India.
  • Gangakhedkar RR; Division of Epidemiology & Communicable Diseases, Indian Council of Medical Research, New Delhi, India.
  • Reddy DCS; Independent Consultant, Lucknow, Uttar Pradesh, India.
Indian J Med Res ; 151(5): 419-423, 2020 May.
Article in English | MEDLINE | ID: covidwho-626319
ABSTRACT
Conducting population-based serosurveillance for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) will estimate and monitor the trend of infection in the adult general population, determine the socio-demographic risk factors and delineate the geographical spread of the infection. For this purpose, a serial cross-sectional survey would be conducted with a sample size of 24,000 distributed equally across four strata of districts categorized on the basis of the incidence of reported cases of COVID-19. Sixty districts will be included in the survey. Simultaneously, the survey will be done in 10 high-burden hotspot cities. ELISA-based antibody tests would be used. Data collection will be done using a mobile-based application. Prevalence from the group of districts in each of the four strata will be pooled to estimate the population prevalence of COVID-19 infection, and similarly for the hotspot cities, after adjusting for demographic characteristics and antibody test performance. The total number of reported cases in the districts and hotspot cities will be adjusted using this seroprevalence to estimate the expected number of infected individuals in the area. Such serosurveys repeated at regular intervals can also guide containment measures in respective areas. State-specific context of disease burden, priorities and resources should guide the use of multifarious surveillance options for the current COVID-19 epidemic.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Population Surveillance / Coronavirus Infections / Betacoronavirus / Antibodies, Viral Type of study: Experimental Studies / Observational study / Prognostic study / Qualitative research / Randomized controlled trials Limits: Female / Humans / Male Country/Region as subject: Asia Language: English Journal: Indian J Med Res Year: 2020 Document Type: Article Affiliation country: Ijmr.IJMR_1818_20

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Population Surveillance / Coronavirus Infections / Betacoronavirus / Antibodies, Viral Type of study: Experimental Studies / Observational study / Prognostic study / Qualitative research / Randomized controlled trials Limits: Female / Humans / Male Country/Region as subject: Asia Language: English Journal: Indian J Med Res Year: 2020 Document Type: Article Affiliation country: Ijmr.IJMR_1818_20