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No evidence of vertical transmission of SARS-CoV-2 after induction of labour in an immune-suppressed SARS-CoV-2-positive patient.
Grimminck, Koen; Santegoets, Lindy Anne Maria; Siemens, Frederike Charlotte; Fraaij, Pieter Leendert Alex; Reiss, Irwin Karl Marcel; Schoenmakers, Sam.
  • Grimminck K; Department of Obstetrics and Gynaecology, Reinier de Graaf Gasthuis, Delft, Zuid-Holland, The Netherlands.
  • Santegoets LAM; Department of Obstetrics and Gynaecology, Reinier de Graaf Gasthuis, Delft, Zuid-Holland, The Netherlands.
  • Siemens FC; Department of Obstetrics and Gynaecology, Reinier de Graaf Gasthuis, Delft, Zuid-Holland, The Netherlands.
  • Fraaij PLA; Department of Paediatrics, Subdivision Infectious Diseases and Immunology, Erasmus Medical Center - Sophia, Rotterdam, The Netherlands.
  • Reiss IKM; Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Schoenmakers S; Division of Neonatology, Erasmus Medical Center, Rotterdam, The Netherlands.
BMJ Case Rep ; 13(6)2020 Jun 30.
Article in English | MEDLINE | ID: covidwho-626472
ABSTRACT
We present a case of a 38+1 weeks pregnant patient (G1P0) with a proven COVID-19 infection, who was planned for induction of labour because of pre-existent hypertension, systemic lupus erythematosus, respiratory problem of coughing and mild dyspnoea without fever during the COVID-19 pandemic in March 2020. To estimate the risk of vertical transmission of Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) during labour and delivery, we collected oropharyngeal, vaginal, urinary, placental and neonatal PCRs for SARS-CoV-2 during the period of admission. All PCRs, except for the oropharyngeal, were negative and vertical transmission was not observed. Labour and delivery were uncomplicated and the patient and neonate were discharged the next day. We give a short overview of the known literature about SARS-CoV-2-related infection during pregnancy, delivery and outcome of the neonate.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Pregnancy Complications, Infectious / Immunocompromised Host / Coronavirus Infections / Infectious Disease Transmission, Vertical Type of study: Case report / Diagnostic study / Prognostic study Limits: Adult / Female / Humans / Infant, Newborn / Pregnancy Language: English Year: 2020 Document Type: Article Affiliation country: Bcr-2020-235581

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Pregnancy Complications, Infectious / Immunocompromised Host / Coronavirus Infections / Infectious Disease Transmission, Vertical Type of study: Case report / Diagnostic study / Prognostic study Limits: Adult / Female / Humans / Infant, Newborn / Pregnancy Language: English Year: 2020 Document Type: Article Affiliation country: Bcr-2020-235581