Potential Treatments for COVID-19 Related Cytokine Storm - Beyond Corticosteroids.

Miao, Yi; Fan, Lei; Li, Jian-Yong

Miao, Yi; Fan, Lei; Li, Jian-Yong.

Miao Y; Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China.
Fan L; Key Laboratory of Hematology of Nanjing Medical University, Nanjing, China.
Li JY; Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China.

Front Immunol ; 11: 1445, 2020.

Article in English | MEDLINE | ID: covidwho-627006

Subject(s)

Antibodies, Monoclonal, Humanized/therapeutic use; Coronavirus Infections/drug therapy; Cytokine Release Syndrome/drug therapy; Etoposide/therapeutic use; Immunomodulation/drug effects; Pneumonia, Viral/drug therapy; Pyrazoles/therapeutic use; Adrenal Cortex Hormones/therapeutic use; Antiviral Agents/therapeutic use; Betacoronavirus/immunology; COVID-19; Coronavirus Infections/blood; Coronavirus Infections/pathology; Cytokine Release Syndrome/immunology; Cytokine Release Syndrome/pathology; Cytokines/blood; Humans; Immunomodulation/immunology; Interleukin-6/antagonists & inhibitors; Lymphohistiocytosis, Hemophagocytic/drug therapy; Lymphohistiocytosis, Hemophagocytic/pathology; Nitriles; Pandemics; Pneumonia, Viral/blood; Pneumonia, Viral/pathology; Pyrimidines; SARS-CoV-2; COVID-19 Drug Treatment

Keywords

COVID-19; IL-6; hemophagocytic lymphohistiocytosis; ruxolitinib; tocilizumab

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Pyrazoles / Coronavirus Infections / Etoposide / Immunomodulation / Antibodies, Monoclonal, Humanized / Cytokine Release Syndrome Limits: Humans Language: English Journal: Front Immunol Year: 2020 Document Type: Article Affiliation country: Fimmu.2020.01445

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