Pulmonary Edema in COVID19-A Neural Hypothesis.
ACS Chem Neurosci
; 11(14): 2048-2050, 2020 07 15.
Article
in English
| MEDLINE | ID: covidwho-627315
ABSTRACT
In COVID-19, lung manifestations present as a slowly evolving pneumonia with insidious early onset interstitial pulmonary edema that undergoes acute exacerbation in the late stages and microvascular thrombosis. Currently, these manifestations are considered to be only consequences of pulmonary SARS-CoV-2 virus infection. We are proposing a new hypothesis that neurogenic insult may also play a major role in the pathogenesis of these manifestations. SARS-CoV-2 mediated inflammation of the nucleus tractus solitarius (NTS) may play a role in the acute exacerbation of pulmonary edema and microvascular clotting in COVID-19 patients.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Pulmonary Edema
/
Thrombosis
/
Solitary Nucleus
/
Coronavirus Infections
/
Microvessels
/
Hypotension
/
Lung
Limits:
Humans
Language:
English
Journal:
ACS Chem Neurosci
Year:
2020
Document Type:
Article
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