The spectrum of COVID-19-associated dermatologic manifestations: An international registry of 716 patients from 31 countries.
J Am Acad Dermatol
; 83(4): 1118-1129, 2020 Oct.
Article
in English
| MEDLINE | ID: covidwho-628238
Preprint
This scientific journal article is probably based on a previously available preprint. It has been identified through a machine matching algorithm, human confirmation is still pending.
See preprint
This scientific journal article is probably based on a previously available preprint. It has been identified through a machine matching algorithm, human confirmation is still pending.
See preprint
ABSTRACT
BACKGROUND:
Coronavirus disease 2019 (COVID-19) has associated cutaneous manifestations.OBJECTIVE:
To characterize the diversity of cutaneous manifestations of COVID-19 and facilitate understanding of the underlying pathophysiology.METHODS:
Case series from an international registry from the American Academy of Dermatology and International League of Dermatological Societies.RESULTS:
The registry collected 716 cases of new-onset dermatologic symptoms in patients with confirmed/suspected COVID-19. Of the 171 patients in the registry with laboratory-confirmed COVID-19, the most common morphologies were morbilliform (22%), pernio-like (18%), urticarial (16%), macular erythema (13%), vesicular (11%), papulosquamous (9.9%), and retiform purpura (6.4%). Pernio-like lesions were common in patients with mild disease, whereas retiform purpura presented exclusively in ill, hospitalized patients.LIMITATIONS:
We cannot estimate incidence or prevalence. Confirmation bias is possible.CONCLUSIONS:
This study highlights the array of cutaneous manifestations associated with COVID-19. Many morphologies were nonspecific, whereas others may provide insight into potential immune or inflammatory pathways in COVID-19 pathophysiology.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Skin Diseases
/
Registries
/
Coronavirus Infections
/
Betacoronavirus
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Topics:
Long Covid
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Middle aged
/
Young adult
Language:
English
Journal:
J Am Acad Dermatol
Year:
2020
Document Type:
Article
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