Targeting inflammation and cytokine storm in COVID-19.

Huang, Qianwen; Wu, Xiumei; Zheng, Xueying; Luo, Sihui; Xu, Suowen; Weng, Jianping

Huang, Qianwen; Wu, Xiumei; Zheng, Xueying; Luo, Sihui; Xu, Suowen; Weng, Jianping.

Huang Q; Department of Endocrinology and Metabolism, Guangdong Provincial Key Laboratory of Diabetology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Wu X; Department of Endocrinology and Metabolism, Guangdong Provincial Key Laboratory of Diabetology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Zheng X; Department of Endocrinology, First Affiliated Hospital, Division of Life Sciences and Medicine, University of Science and Technology of China (USTC), Hefei, China.
Luo S; Department of Endocrinology, First Affiliated Hospital, Division of Life Sciences and Medicine, University of Science and Technology of China (USTC), Hefei, China.
Xu S; Department of Endocrinology, First Affiliated Hospital, Division of Life Sciences and Medicine, University of Science and Technology of China (USTC), Hefei, China. Electronic address: sxu1984@ustc.edu.cn.
Weng J; Department of Endocrinology, First Affiliated Hospital, Division of Life Sciences and Medicine, University of Science and Technology of China (USTC), Hefei, China. Electronic address: wengjp@ustc.edu.cn.

Pharmacol Res ; 159: 105051, 2020 09.

Article in English | MEDLINE | ID: covidwho-628448

Subject(s)

Betacoronavirus; Coronavirus Infections/drug therapy; Cytokines/metabolism; Inflammation/drug therapy; Pneumonia, Viral/drug therapy; Anti-Inflammatory Agents/therapeutic use; COVID-19; Cell Cycle Proteins/antagonists & inhibitors; Coronavirus Infections/immunology; Coronavirus Infections/virology; Host Microbial Interactions/drug effects; Host Microbial Interactions/immunology; Humans; Immunologic Factors/therapeutic use; Inflammasomes/drug effects; Inflammasomes/immunology; Inflammation/immunology; Inflammation/virology; Interleukin-6/antagonists & inhibitors; Models, Immunological; NLR Family, Pyrin Domain-Containing 3 Protein/antagonists & inhibitors; Pandemics; Pneumonia, Viral/immunology; Pneumonia, Viral/virology; SARS-CoV-2; Transcription Factors/antagonists & inhibitors; COVID-19 Drug Treatment

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Cytokines / Coronavirus Infections / Betacoronavirus / Inflammation Limits: Humans Language: English Journal: Pharmacol Res Journal subject: Pharmacology Year: 2020 Document Type: Article Affiliation country: J.phrs.2020.105051

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