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Correlations between COVID-19 and burden of dementia: An ecological study and review of literature.
Azarpazhooh, M Reza; Amiri, Amin; Morovatdar, Negar; Steinwender, Sandy; Rezaei Ardani, Amir; Yassi, Nawaf; Biller, Jose; Stranges, Saverio; Tokazebani Belasi, Masoud; Neya, Sepideh Kazemi; Khorram, Bita; Sheikh Andalibi, Mohammad Sobhan; Arsang-Jang, Shahram; Mokhber, Naghmeh; Di Napoli, Mario.
  • Azarpazhooh MR; Stroke Prevention and Atherosclerosis Research Centre, Robarts Research Institute, Western University, London, Ontario, Canada; Department of Clinical Neurological Sciences, Western University, London, Ontario, Canada; Department of Epidemiology and Biostatistics, Schulich School of Medicine & D
  • Amiri A; Department of Neurology, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Morovatdar N; Clinical Research Development Unit, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Steinwender S; Health Information Science, PhD (candidate) Western University, London, Ontario, Canada. Electronic address: ssteinwe@uwo.ca.
  • Rezaei Ardani A; Psychiatry and Behavioural Sciences Research Centre, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address: rezaeia@mums.ac.ir.
  • Yassi N; Departments of Medicine and Neurology, Melbourne Brain Centre at The Royal Melbourne Hospital, University of Melbourne, Parkville, Australia; Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Australia. Electronic address: nawaf.yassi@unimel
  • Biller J; Department of Neurology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, USA. Electronic address: jbiller@lumc.edu.
  • Stranges S; Department of Epidemiology and Biostatistics, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada; Department of Family Medicine Schulich School of Medicine, Dentistry Western University, London, ON, Canada; Department of Population Health, Luxembourg Institute o
  • Tokazebani Belasi M; Research Centre for Prevention of cardiovascular disease, Institute of Endocrinology & Metabolism, Iran University of Medical Sciences, Tehran, Iran. Electronic address: mtokazebani@gmail.com.
  • Neya SK; Research Centre for Prevention of cardiovascular disease, Institute of Endocrinology & Metabolism, Iran University of Medical Sciences, Tehran, Iran. Electronic address: sepideh.kazeminia@gmail.com.
  • Khorram B; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada. Electronic address: bita.khorram@mail.utoronto.ca.
  • Sheikh Andalibi MS; International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address: mssha96@gmail.com.
  • Arsang-Jang S; Department of Biostatistics and Epidemiology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
  • Mokhber N; Department of Psychiatry, St Joseph's Health Care London, Western University, Canada. Electronic address: Naghmeh.Mokhber@sjhc.london.on.ca.
  • Di Napoli M; Department of Neurology and Stroke Unit, San Camillo de' Lellis General District Hospital, Rieti, Italy; Neurological Section, Neuro-epidemiology Unit, SMDN-Centre for Cardiovascular Medicine and Cerebrovascular Disease Prevention, Sulmona, L'Aquila, Italy. Electronic address: mariodinapoli@katamail
J Neurol Sci ; 416: 117013, 2020 09 15.
Article in English | MEDLINE | ID: covidwho-629733
ABSTRACT

INTRODUCTION:

Current evidence on the association between COVID-19 and dementia is sparse. This study aims to investigate the associations between COVID-19 caseload and the burden of dementia.

METHODS:

We gathered data regarding burden of dementia (disability-adjusted life years [DALYs] per 100,000), life expectancy, and healthy life expectancy (HALE) from the Global Burden of Disease (GBD) 2017 study. We obtained COVID-19 data from Our World in Data database. We analyzed the association of COVID-19 cases and deaths with the burden of dementia using Spearman's rank correlation coefficient.

RESULTS:

Globally, we found significant positive (p < .001) correlations between life expectancy (r = 0.60), HALE (r = 0.58), and dementia DALYs (r = 0.46) with COVID-19 caseloads. Likewise, we found similar correlations between life expectancy (r = 0.60), HALE (r = 0.58) and dementia DALYs (r = 0.54) with COVID-19 mortality.

CONCLUSION:

Health policymakers should clarify a targeted model of disease surveillance in order to reduce the dual burden of dementia and COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Dementia / COVID-19 Type of study: Observational study Limits: Humans Language: English Journal: J Neurol Sci Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Dementia / COVID-19 Type of study: Observational study Limits: Humans Language: English Journal: J Neurol Sci Year: 2020 Document Type: Article