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[Preliminary Study on Clinical Features and CT Findings of Common-type Coronavirus Disease 2019 Patients in Peking Union Medical College Hospital].
Song, Lan; Song, Wei; Sui, Xin; DU, Tiekuan; Liu, Wu; Wang, Baiyu; Lu, Xiaoping; Xu, Yan; Yang, Qiwen; Cao, Wei; Jin, Zhengyu.
  • Song L; Department of Radiology.
  • Song W; Department of Radiology.
  • Sui X; Department of Radiology.
  • DU T; Department of Emergency.
  • Liu W; Department of Radiology.
  • Wang B; Department of Radiology.
  • Lu X; Department of Radiology.
  • Xu Y; Department of Respiratory and Critical Care Medicine.
  • Yang Q; Department of Laboratory.
  • Cao W; Department of Infectious Diseases,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
  • Jin Z; Department of Radiology.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao ; 42(3): 376-382, 2020 Jun 30.
Article in Chinese | MEDLINE | ID: covidwho-631729
Semantic information from SemMedBD (by NLM)
1. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
2. Toxic Epidermal Necrolysis PROCESS_OF Patients
Subject
Toxic Epidermal Necrolysis
Predicate
PROCESS_OF
Object
Patients
3. Fever PROCESS_OF Patients
Subject
Fever
Predicate
PROCESS_OF
Object
Patients
4. Lesion PROCESS_OF Patients
Subject
Lesion
Predicate
PROCESS_OF
Object
Patients
5. Multiple lesions PROCESS_OF Patients
Subject
Multiple lesions
Predicate
PROCESS_OF
Object
Patients
6. Both lungs LOCATION_OF Multiple lesions
Subject
Both lungs
Predicate
LOCATION_OF
Object
Multiple lesions
7. Bronchial wall thickening COEXISTS_WITH Lesion
Subject
Bronchial wall thickening
Predicate
COEXISTS_WITH
Object
Lesion
8. Dry cough PROCESS_OF Patients
Subject
Dry cough
Predicate
PROCESS_OF
Object
Patients
9. Lung LOCATION_OF Ground Glass Opacity
Subject
Lung
Predicate
LOCATION_OF
Object
Ground Glass Opacity
10. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
11. Toxic Epidermal Necrolysis PROCESS_OF Patients
Subject
Toxic Epidermal Necrolysis
Predicate
PROCESS_OF
Object
Patients
12. Fever PROCESS_OF Patients
Subject
Fever
Predicate
PROCESS_OF
Object
Patients
13. Lesion PROCESS_OF Patients
Subject
Lesion
Predicate
PROCESS_OF
Object
Patients
14. Multiple lesions PROCESS_OF Patients
Subject
Multiple lesions
Predicate
PROCESS_OF
Object
Patients
15. Both lungs LOCATION_OF Multiple lesions
Subject
Both lungs
Predicate
LOCATION_OF
Object
Multiple lesions
16. Bronchial wall thickening COEXISTS_WITH Lesion
Subject
Bronchial wall thickening
Predicate
COEXISTS_WITH
Object
Lesion
17. Dry cough PROCESS_OF Patients
Subject
Dry cough
Predicate
PROCESS_OF
Object
Patients
18. Lung LOCATION_OF Ground Glass Opacity
Subject
Lung
Predicate
LOCATION_OF
Object
Ground Glass Opacity
ABSTRACT
Objective To summarize the clinical characteristics and chest CT findings of coronavirus disease 2019(COVID-19)patients in Peking Union Medical College Hospital(PUMCH). Methods A total of 13 patients with COVID-19 confirmed at PUMCH from January 20 to February 6,2020 were selected as the research subjects.Their epidemiological histories,clinical characteristics,laboratory tests,and chest CT findings were analyzed retrospectively.The location,distribution,density,and other accompanying signs of abnormal lung CT lesions were recorded,and the clinical types of these patients were assessed. Results The clinical type was "common type" in all these 13 patients aged(46.8±14.7)years(range27-68 years).Ten patients had a travel history to Wuhan or direct contact with patients from Wuhan,2 cases had recent travel histories,and 1 case had a travel history to Beijing suburb.The white blood cell(WBC)count was normal or decreased in 92.3% of the patients and the lymphocyte count decreased in 15.4% of the patients.Twelve patients(92.3%)had a fever,among whom 11 patients were admitted due to fever and 2 patients(15.4%)had low fever.Eight patients(61.5%)had dry cough.The CT findings in these 13 patients were all abnormal.The lesions were mainly distributed along the bronchi and under the pleura.The lesions were relatively limited in 8 patients(affecting 1-3 lobes,predominantly in the right or left lower lobe),and diffuse multiple lesions of bilateral lungs were seen in 5 patients.The CT findings mainly included ground glass opacities(GGOs)(n=10,76.9%),focal consolidation within GGOs(n=7,53.8%),thickened vascular bundle passing through the lesions(n=10,76.9%),bronchial wall thickening(n=12,92.3%),air bronchogram(n=10,76.9%),vacuole signs in the lesions(n=7,53.8%),fine reticulation and interlobular septal thickening(n=3,23.1%),reversed halo-sign(n=2,15.4%),crazy-paving pattern(n=2,15.4%),and pleural effusion(n=2,15.4%).Conclusions Most of our patients diagnosed with COVID-19 at PUMCH had a travel history to Wuhan or direct contact with patients from Wuhan.The first symptoms of COVID-19 mainly include fever and dry cough,along with normal or reduced counts of WBC and lymphocytes.CT may reveal that the lesions distribute along the bronchi and under the pleura;they are typically localized GGOs in the early stage but can become multiple GGOs and infiltrative consolidation in both lungs in the advanced stage.Scattered vacuole signs may be visible inside the lesions in some patients.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Pandemics / Betacoronavirus Type of study: Diagnostic study / Observational study Limits: Adult / Aged / Humans / Middle aged Language: Chinese Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao Year: 2020 Document Type: Article

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Pandemics / Betacoronavirus Type of study: Diagnostic study / Observational study Limits: Adult / Aged / Humans / Middle aged Language: Chinese Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao Year: 2020 Document Type: Article