Mild encephalopathy with reversible splenium lesion (MERS) in a patient with COVID-19.
J Clin Neurosci
; 79: 272-274, 2020 Sep.
Article
in English
| MEDLINE | ID: covidwho-634295
ABSTRACT
Neurological complications of coronavirus 2019 (COVID-19) are common, and novel manifestations are increasingly being recognized. Mild encephalopathy with reversible splenium lesion (MERS) is a syndrome that has been associated with viral infections, but not previously with COVID-19. In this report, we describe the case of a 69 year-old man who presented with fever and encephalopathy in the setting of a diffusion-restricting splenium lesion, initially mimicking an ischemic stroke. A comprehensive infectious workup revealed positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies, and a pro-inflammatory laboratory profile characteristic of COVID-19 infection. His symptoms resolved and the brain MRI findings completely normalized on repeat imaging, consistent with MERS. This case suggests that MERS may manifest as an autoimmune response to SARS-CoV-2 infection and should be considered in a patient with evidence of recent COVID-19 infection and the characteristic MERS clinico-radiological syndrome.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Brain Diseases
/
Coronavirus Infections
/
Paraspinal Muscles
/
Betacoronavirus
Type of study:
Case report
Topics:
Long Covid
Limits:
Aged
/
Humans
/
Male
Language:
English
Journal:
J Clin Neurosci
Journal subject:
Neurology
Year:
2020
Document Type:
Article
Affiliation country:
J.jocn.2020.07.009
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