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Is continuous positive airway pressure (CPAP) a new standard of care for type 1 respiratory failure in COVID-19 patients? A retrospective observational study of a dedicated COVID-19 CPAP service.
Nightingale, Rebecca; Nwosu, Nneka; Kutubudin, Farheen; Fletcher, Tom; Lewis, Joe; Frost, Frederick; Haigh, Kathryn; Robinson, Ryan; Kumar, Ayesha; Jones, Gareth; Brown, Deborah; Abouyannis, Michael; Beadsworth, Mike; Hampshire, Peter; Aston, Stephen; Gautam, Manish; Burhan, Hassan.
  • Nightingale R; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK rebecca.nightingale@lstmed.ac.uk.
  • Nwosu N; Department of Respiratory Medicine, Tropical and Infectious Disease Unit, Intensive Care Unit, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Kutubudin F; Department of Respiratory Medicine, Tropical and Infectious Disease Unit, Intensive Care Unit, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Fletcher T; Department of Respiratory Medicine, Tropical and Infectious Disease Unit, Intensive Care Unit, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Lewis J; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.
  • Frost F; Department of Respiratory Medicine, Tropical and Infectious Disease Unit, Intensive Care Unit, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Haigh K; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.
  • Robinson R; Department of Respiratory Medicine, Tropical and Infectious Disease Unit, Intensive Care Unit, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Kumar A; Institute of Infection and Global Health, University of Liverpool, Liverpool, Merseyside, UK.
  • Jones G; Department of Respiratory Medicine, Tropical and Infectious Disease Unit, Intensive Care Unit, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Brown D; Institute of Infection and Global Health, University of Liverpool, Liverpool, Merseyside, UK.
  • Abouyannis M; Department of Respiratory Medicine, Tropical and Infectious Disease Unit, Intensive Care Unit, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Beadsworth M; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.
  • Hampshire P; Department of Respiratory Medicine, Tropical and Infectious Disease Unit, Intensive Care Unit, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Aston S; Department of Respiratory Medicine, Tropical and Infectious Disease Unit, Intensive Care Unit, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Gautam M; Department of Respiratory Medicine, Tropical and Infectious Disease Unit, Intensive Care Unit, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Burhan H; Department of Respiratory Medicine, Tropical and Infectious Disease Unit, Intensive Care Unit, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
BMJ Open Respir Res ; 7(1)2020 07.
Article in English | MEDLINE | ID: covidwho-634563
ABSTRACT
The aim of this case series is to describe and evaluate our experience of continuous positive airway pressure (CPAP) to treat type 1 respiratory failure in patients with COVID-19. CPAP was delivered in negative pressure rooms in the newly repurposed infectious disease unit. We report a cohort of 24 patients with type 1 respiratory failure and COVID-19 admitted to the Royal Liverpool Hospital between 1 April and 30 April 2020. Overall, our results were positive; we were able to safely administer CPAP outside the walls of a critical care or high dependency unit environment and over half of patients (58%) avoided mechanical ventilation and a total of 19 out of 24 (79%) have survived and been discharged from our care.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Respiratory Care Units / Respiratory Insufficiency / Coronavirus Infections / Continuous Positive Airway Pressure / Pandemics / Procedures and Techniques Utilization Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study Limits: Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Year: 2020 Document Type: Article Affiliation country: Bmjresp-2020-000639

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Respiratory Care Units / Respiratory Insufficiency / Coronavirus Infections / Continuous Positive Airway Pressure / Pandemics / Procedures and Techniques Utilization Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study Limits: Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Year: 2020 Document Type: Article Affiliation country: Bmjresp-2020-000639