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A single-centre experience of intravenous thrombolysis for stroke in COVID-19 patients.
Sangalli, Davide; Polonia, Valeria; Colombo, Daniele; Mantero, Vittorio; Filizzolo, Marco; Scaccabarozzi, Chiara; Salmaggi, Andrea.
  • Sangalli D; Unit of Neurology, "Alessandro Manzoni" Hospital - ASST Lecco, Via dell'Eremo 9/11, 23900, Lecco, Italy. d.sangalli@asst-lecco.it.
  • Polonia V; Unit of Neurology, "Alessandro Manzoni" Hospital - ASST Lecco, Via dell'Eremo 9/11, 23900, Lecco, Italy.
  • Colombo D; University of Milano-Bicocca, Milan, Italy.
  • Mantero V; Unit of Neurology, "Alessandro Manzoni" Hospital - ASST Lecco, Via dell'Eremo 9/11, 23900, Lecco, Italy.
  • Filizzolo M; Unit of Neurology, "Alessandro Manzoni" Hospital - ASST Lecco, Via dell'Eremo 9/11, 23900, Lecco, Italy.
  • Scaccabarozzi C; Unit of Neuroradiology, "Alessandro Manzoni" Hospital - ASST Lecco, Lecco, Italy.
  • Salmaggi A; Unit of Neurology, "Alessandro Manzoni" Hospital - ASST Lecco, Via dell'Eremo 9/11, 23900, Lecco, Italy.
Neurol Sci ; 41(9): 2325-2329, 2020 Sep.
Article in English | MEDLINE | ID: covidwho-640307
ABSTRACT
The sudden worldwide outbreak of Coronavirus Disease 2019 (COVID-19) has certainly provided new challenges in the management of acute ischaemic stroke, and the risk-benefit ratio of intravenous thrombolysis in COVID-19 positive patients is not well known. We describe four COVID-19 patients treated with intravenous thrombolysis for acute ischaemic stroke. Although rt-PA administration is the main therapeutic strategy, our patients experienced unpredictable complications and showed atypical features the overall mortality was very high. In conclusion, in this article, we provide information about these cases and discuss the possible explanation behind this trend.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Thrombolytic Therapy / Brain Ischemia / Tissue Plasminogen Activator / Coronavirus Infections / Stroke / Betacoronavirus Type of study: Case report / Prognostic study Topics: Long Covid Limits: Aged / Female / Humans / Male / Middle aged Language: English Journal: Neurol Sci Journal subject: Neurology Year: 2020 Document Type: Article Affiliation country: S10072-020-04591-3

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Thrombolytic Therapy / Brain Ischemia / Tissue Plasminogen Activator / Coronavirus Infections / Stroke / Betacoronavirus Type of study: Case report / Prognostic study Topics: Long Covid Limits: Aged / Female / Humans / Male / Middle aged Language: English Journal: Neurol Sci Journal subject: Neurology Year: 2020 Document Type: Article Affiliation country: S10072-020-04591-3