Clinical and CT features of the COVID-19 infection: comparison among four different age groups.
Eur Geriatr Med
; 11(5): 843-850, 2020 Oct.
Article
in English
| MEDLINE | ID: covidwho-640776
ABSTRACT
PURPOSE:
To compare and analyze the clinical and CT features of coronavirus disease 2019 (COVID-19) among four different age groups.METHODS:
97 patients (45 males, 52 females, mean age, 66.2 ± 5.0) with chest CT examination and positive reverse transcriptase-polymerase chain reaction test (RT-PCR) from January 17, 2020 to February 21, 2020 were retrospectively studied. The patients were divided into four age groups (children [0-17 years], young adults [18-44 years], middle age [45-59 years], and senior [≥ 60 years]) according to their age after the diagnosis was made based on PCR test and clinical symptoms.RESULTS:
Comorbidities such as hypertension, diabetes mellitus, and heart disease are more common in the senior group. Cluster onset (two or more confirmed cases in a small area) is more common in the children group and senior group. Older patients were found to have a higher incidence of the highest clinical classification (severe or critical) in these four groups. Senior patients have a higher incidence of large/multiple ground-glass opacity (GGO). Child patients are mostly negative for chest CT or with involvement of only one lobe of the lung; while in older patients, there was a higher incidence of involvement of four or five lung lobes. The frequency of lobe involvement was also found to have significant differences in the four age groups.CONCLUSION:
The clinical and imaging features of patients in different age groups were found to be significantly different. A better understanding of the age differences in comorbidities, cluster onset, highest clinical classification, large/multiple GGO, numbers of lobes affected, and frequency of lobe involvement can be useful in the diagnosis of COVID-19 patients of different ages.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Tomography, X-Ray Computed
/
Coronavirus Infections
/
Pandemics
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Adolescent
/
Adult
/
Aged
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Middle aged
Language:
English
Journal:
Eur Geriatr Med
Year:
2020
Document Type:
Article
Affiliation country:
S41999-020-00356-5
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