A Low Viral Dose in COVID-19 Patient: A Case Report.
Front Public Health
; 8: 339, 2020.
Article
in English
| MEDLINE | ID: covidwho-646611
ABSTRACT
SARS-CoV-2 outbreak has attracted global attention. Verifying the presence of viral RNA is the gold standard for the diagnosis of COVID-19. However, RT-qPCR diagnosis often fails to catch infected patients, because of inconsistent swab sample collection. Here we report a case that showed 5 consecutive negative and 1 low-viral- dose RT-qPCR results during illness spanning over 20 days. Clinical symptoms suggest SARS-CoV-2 infection with typical ground glass like a lung in computed tomography. SARS-CoV-2 infection was serologically confirmed by the presence of anti-SARS-CoV-2 specific antibodies in patients' serum. Finally, a high level of protective IgG was produced after the patient recovered. Surprisingly, as a barber and a housewife staying at home for the first 2 weeks after the onset of illness, none of the close contacts were infected, showing a case of low viral load and low infectivity in this patient.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
Type of study:
Case report
/
Diagnostic study
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Front Public Health
Year:
2020
Document Type:
Article
Affiliation country:
Fpubh.2020.00339
Similar
MEDLINE
...
LILACS
LIS