Can the Environmental Phagocyte Acanthamoeba Be a Useful Model to Study SARS-CoV-2 Pathogenicity, Infectivity, and Evasion of Cellular Immune Defenses?
ACS Chem Neurosci
; 11(15): 2149-2151, 2020 08 05.
Article
in English
| MEDLINE | ID: covidwho-646953
ABSTRACT
Acanthamoeba and macrophages exhibit significant parallels in biochemical, physiological, cellular, and functional aspects. Given the ability of Acanthamoeba to contribute to the evolutionary gain of pathogenicity of a variety of microbial pathogens, here we propose the use of Acanthamoeba as a paradigm to study SARS-CoV-2 pathogenicity, infectivity, and evasion of cellular immune defenses.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Phagocytes
/
Pneumonia, Viral
/
Acanthamoeba
/
Coronavirus Infections
/
Betacoronavirus
/
Immunity, Cellular
Limits:
Animals
/
Humans
Language:
English
Journal:
ACS Chem Neurosci
Year:
2020
Document Type:
Article
Affiliation country:
Acschemneuro.0c00401
Similar
MEDLINE
...
LILACS
LIS