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Increased expression of ACE2, the SARS-CoV-2 entry receptor, in alveolar and bronchial epithelium of smokers and COPD subjects.
Jacobs, Merel; Van Eeckhoutte, Hannelore P; Wijnant, Sara R A; Janssens, Wim; Joos, Guy F; Brusselle, Guy G; Bracke, Ken R.
  • Jacobs M; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Dept of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.
  • Van Eeckhoutte HP; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Dept of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.
  • Wijnant SRA; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Dept of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.
  • Janssens W; Dept of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Joos GF; Dept of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.
  • Brusselle GG; Respiratory Division and Rehabilitation, University Hospital Leuven, Leuven, Belgium.
  • Bracke KR; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Dept of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.
Eur Respir J ; 56(2)2020 08.
Article in English | MEDLINE | ID: covidwho-652704
Preprint
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Semantic information from SemMedBD (by NLM)
1. Epithelium of bronchus LOCATION_OF ACE2 gene|ACE2
Subject
Epithelium of bronchus
Predicate
LOCATION_OF
Object
ACE2 gene|ACE2
2. Alveolar LOCATION_OF ACE2 gene|ACE2
Subject
Alveolar
Predicate
LOCATION_OF
Object
ACE2 gene|ACE2
3. Epithelium of bronchus LOCATION_OF ACE2 gene|ACE2
Subject
Epithelium of bronchus
Predicate
LOCATION_OF
Object
ACE2 gene|ACE2
4. Alveolar LOCATION_OF ACE2 gene|ACE2
Subject
Alveolar
Predicate
LOCATION_OF
Object
ACE2 gene|ACE2

Full text: Available Collection: International databases Database: MEDLINE Main subject: RNA, Messenger / Smoking / Peptidyl-Dipeptidase A / Respiratory Mucosa / Pulmonary Disease, Chronic Obstructive / Betacoronavirus Type of study: Diagnostic study / Prevalence study / Prognostic study / Randomized controlled trials / Risk factors Limits: Female / Humans / Male Country/Region as subject: Europa Language: English Year: 2020 Document Type: Article Affiliation country: 13993003.02378-2020

Full text: Available Collection: International databases Database: MEDLINE Main subject: RNA, Messenger / Smoking / Peptidyl-Dipeptidase A / Respiratory Mucosa / Pulmonary Disease, Chronic Obstructive / Betacoronavirus Type of study: Diagnostic study / Prevalence study / Prognostic study / Randomized controlled trials / Risk factors Limits: Female / Humans / Male Country/Region as subject: Europa Language: English Year: 2020 Document Type: Article Affiliation country: 13993003.02378-2020