Your browser doesn't support javascript.
Epidemiologic and clinical characteristics of 10 children with coronavirus disease 2019 in Changsha, China.
Tan, Yu-Pin; Tan, Bo-Yu; Pan, Jia; Wu, Jing; Zeng, Sai-Zhen; Wei, Hong-Yan.
  • Tan YP; Division of Pediatrics, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, 410005, PR China. Electronic address: tan_yupin@163.com.
  • Tan BY; Division of Clinical Pharmacy, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, Hunan, 410005, PR China. Electronic address: tanboyu@hunnu.edu.cn.
  • Pan J; Division of Gastroenterology, Changsha Public Health Rescue Center, North Hospital of Changsha First Hospital, Changsha, 410005, PR China. Electronic address: 344845032@qq.com.
  • Wu J; Division of Pharmacy, College of Medicine, Hunan Normal University, Changsha, 410005, PR China; Division of Clinical Pharmacy, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, Hunan, 410005, PR China. Electronic address: 474921585@qq.com.
  • Zeng SZ; Division of Pediatrics, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, 410005, PR China. Electronic address: 55445321@qq.com.
  • Wei HY; Division of Clinical Pharmacy, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, Hunan, 410005, PR China. Electronic address: weihongyan@hunnu.edu.cn.
J Clin Virol ; 127: 104353, 2020 06.
Article in English | MEDLINE | ID: covidwho-65320
ABSTRACT

BACKGROUND:

The outbreak of a new coronavirus, first reported in Wuhan, China, is spreading around the world. Information on the characteristics of children with Coronavirus Disease 2019 (COVID-19) is limited.

METHODS:

In this retrospective study, we recruited 10 children infected with SARS-COV-2 from January 27 to March 10, 2020, in Changsha, China. We report the epidemiological, clinical, laboratory, and high-resolution CT findings for these children. Qualitative descriptive analysis was used to describe the key results.

RESULTS:

Ten children were included. Three were male and seven were female. Three were from Wuhan, Hubei Province, and seven were from Changsha. All had a history of close contact with adults with COVID-19 before the onset of disease. Clinical manifestations included fever in four cases, respiratory symptoms in three cases, febrile convulsions in one case, vomiting in one case, abdominal pain in one case, and asymptomatic infection in two cases. All the children tested positive for nucleic acid in throat swabs at admission. Stool swabs of three cases were positive for nucleic acid after several days of fever. In nine children, blood routine results were normal, whereas in one case the white blood cell count was elevated. In four cases, CT findings of the lungs showed light ground-glass opacities, one case showed changes similar to bronchopneumonia, and the remaining cases were normal. All were treated with symptomatic support without complications.

CONCLUSION:

Our findings indicate that intrafamily transmission may be the main form of transmission of COVID-19 in children, and persistent intestinal excretion of virus is another characteristic among children. The results of stool swab tests should be considered for discharge and release from isolation.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Feces / Lung Type of study: Diagnostic study / Observational study / Prognostic study / Qualitative research Topics: Long Covid Limits: Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: Asia Language: English Journal: J Clin Virol Journal subject: Virology Year: 2020 Document Type: Article

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Feces / Lung Type of study: Diagnostic study / Observational study / Prognostic study / Qualitative research Topics: Long Covid Limits: Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: Asia Language: English Journal: J Clin Virol Journal subject: Virology Year: 2020 Document Type: Article