SARS-CoV-2 T cell immunity: Specificity, function, durability, and role in protection.
Sci Immunol
; 5(49)2020 07 17.
Article
in English
| MEDLINE | ID: covidwho-654245
ABSTRACT
In efforts to synthesize a clear understanding of SARS-CoV-2 protective immunity, antibody analysis has been paralleled by T cell studies across asymptomatic, mild and severe COVID-19. Defining CD4 and CD8 effector functions in protection is important considering that antibody responses appear short-lived and T cell memory is potentially more durable. To fully understand population level immunity, screening for both antibody and T cell immunity using standardized testing methods would be beneficial.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
CD4-Positive T-Lymphocytes
/
Coronavirus Infections
/
CD8-Positive T-Lymphocytes
/
Antibodies, Neutralizing
/
Betacoronavirus
/
Antibodies, Viral
Limits:
Humans
Language:
English
Year:
2020
Document Type:
Article
Affiliation country:
Sciimmunol.abd6160
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