Why continuing uncertainties are no reason to postpone challenge trials for coronavirus vaccines.
J Med Ethics
; 46(12): 808-812, 2020 12.
Article
in English
| MEDLINE | ID: covidwho-654957
ABSTRACT
To counter the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), some have proposed accelerating SARS-CoV-2 vaccine development through controlled human infection (or 'challenge') trials. These trials would involve the deliberate exposure of relatively few young, healthy volunteers to SARS-CoV-2. We defend this proposal against the charge that there is still too much uncertainty surrounding the risks of COVID-19 to responsibly run such a trial.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Clinical Trials as Topic
/
Biomedical Research
/
COVID-19 Vaccines
/
COVID-19
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Topics:
Vaccines
Limits:
Humans
Language:
English
Journal:
J Med Ethics
Year:
2020
Document Type:
Article
Affiliation country:
Medethics-2020-106501
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