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Risk factors associated with occurrence of COVID-19 among household persons exposed to patients with confirmed COVID-19 in Qingdao Municipal, China.
Xin, Hualei; Jiang, Fachun; Xue, Aili; Liang, Jiwei; Zhang, Jingfei; Yang, Feng; Han, Yalin.
  • Xin H; Qingdao Municipal Centre for Disease Control and Prevention, Qingdao City, China.
  • Jiang F; Qingdao Institute of Prevention Medicine, Qingdao City, China.
  • Xue A; Qingdao Municipal Centre for Disease Control and Prevention, Qingdao City, China.
  • Liang J; Qingdao Institute of Prevention Medicine, Qingdao City, China.
  • Zhang J; Qingdao Women and Children's Hospital, Qingdao City, China.
  • Yang F; Qingdao Municipal Centre for Disease Control and Prevention, Qingdao City, China.
  • Han Y; Qingdao Institute of Prevention Medicine, Qingdao City, China.
Transbound Emerg Dis ; 68(2): 782-788, 2021 Mar.
Article in English | MEDLINE | ID: covidwho-657344
ABSTRACT
Tracing and isolation of close contacts is used to control outbreaks of coronavirus disease 2019 (COVID-19) in China. However, risk factors associated with the occurrence of COVID-19 among close contacts have not been well described. A total of 106 household contacts were included in this study, of whom 19 developed into COVID-19 cases, and the secondary attack rate was 17.9%. Multivariable analysis showed that increasing risk of occurrence of COVID-19 among household contacts was associated with female index patients (adjusted hazard ratio [aHR] = 3.84, 95% CI = 1.07-13.78), critical disease index patients (aHR = 7.58, 95% CI = 1.66-34.66), effective contact duration with index patients > 2 days (aHR = 4.21, 95% CI = 1.29-13.73), and effective contact duration > 11 days (aHR = 17.88, 95% CI = 3.26-98.01). The sex and disease severity of index patients with COVID-19 and longer effective contact duration with patients with confirmed COVID-19 could help epidemiologists to identify potential COVID-19 cases among household contacts at an early stage.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Family Characteristics / Disease Outbreaks / SARS-CoV-2 / COVID-19 Type of study: Cohort study / Observational study / Prognostic study Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: English Journal: Transbound Emerg Dis Journal subject: Veterinary Medicine Year: 2021 Document Type: Article Affiliation country: Tbed.13743

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Family Characteristics / Disease Outbreaks / SARS-CoV-2 / COVID-19 Type of study: Cohort study / Observational study / Prognostic study Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: English Journal: Transbound Emerg Dis Journal subject: Veterinary Medicine Year: 2021 Document Type: Article Affiliation country: Tbed.13743