The role of autophagy in respiratory complications of COVID-19
Shiraz E Medical Journal
; 21(6):1-3, 2020.
Article
in English
| EMBASE | ID: covidwho-658995
ABSTRACT
Background:
The rapid spreading of corona virus disease 2019 (COVID-19) worldwide results in pneumonia and acute respiratory distress syndrome in many patients, which can be the major cause of death in cases with COVID-19. It has been reported that chloro-quine (CQ) has improved COVID-19-induced pneumonia in clinical trials.Objectives:
Since CQ and its derivatives are proved to exhibit anti-autophagy properties based on previous studies, autophagy can be introduced as a possible mechanism of respiratory complications.Methods:
In the current study, we reviewed papers of Google Scholar database with no time limitation.Results:
It was revealed that autophagy has an important role in the manifestation of COVID-19 respiratory complicationsConclusions:
Autophagy is triggered by SARS-CoV2 virus for its replication and autophagy inhibitory treatments might be consid-ered promising therapeutics.
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Language:
English
Journal:
Shiraz E Medical Journal
Year:
2020
Document Type:
Article
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