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Treating type 2 diabetes in COVID-19 patients: the potential benefits of injective therapies.
Longo, Miriam; Caruso, Paola; Maiorino, Maria Ida; Bellastella, Giuseppe; Giugliano, Dario; Esposito, Katherine.
  • Longo M; Division of Endocrinology and Metabolic Diseases, Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Piazza Luigi Miraglia 2, 80138, Naples, Italy. miriam.longo@unicampania.it.
  • Caruso P; Division of Endocrinology and Metabolic Diseases, Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Piazza Luigi Miraglia 2, 80138, Naples, Italy.
  • Maiorino MI; Diabetes Unit, Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy.
  • Bellastella G; Division of Endocrinology and Metabolic Diseases, Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Piazza Luigi Miraglia 2, 80138, Naples, Italy.
  • Giugliano D; Division of Endocrinology and Metabolic Diseases, Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Piazza Luigi Miraglia 2, 80138, Naples, Italy.
  • Esposito K; Diabetes Unit, Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy.
Cardiovasc Diabetol ; 19(1): 115, 2020 07 22.
Article in English | MEDLINE | ID: covidwho-662457
ABSTRACT
The coronavirus disease 2019 (COVID-19) has been declared as pandemic by the World Health Organization and is causing substantial morbidity and mortality all over the world. Type 2 diabetes, hypertension, and cardiovascular disease significantly increase the risk for hospitalization and death in COVID-19 patients. Hypoglycemia and hyperglycemia are both predictors for adverse outcomes in hospitalized patients. An optimized glycemic control should be pursued in patients with diabetes and SARS-CoV-2 infection in order to reduce the risk of severe COVID-19 course. Both insulin and GLP-1RAs have shown optimal glucose-lowering and anti-inflammatory effects in type 2 diabetic patients and may represent a valid therapeutic option to treat asymptomatic and non-critically ill COVID-19 diabetic patients.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Blood Glucose / Coronavirus Infections / Diabetes Mellitus, Type 2 / Incretins / Betacoronavirus / Hypoglycemic Agents / Insulin Type of study: Diagnostic study / Observational study / Prognostic study Limits: Humans Language: English Journal: Cardiovasc Diabetol Journal subject: Vascular Diseases / Cardiology / Endocrinology Year: 2020 Document Type: Article Affiliation country: S12933-020-01090-9

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Blood Glucose / Coronavirus Infections / Diabetes Mellitus, Type 2 / Incretins / Betacoronavirus / Hypoglycemic Agents / Insulin Type of study: Diagnostic study / Observational study / Prognostic study Limits: Humans Language: English Journal: Cardiovasc Diabetol Journal subject: Vascular Diseases / Cardiology / Endocrinology Year: 2020 Document Type: Article Affiliation country: S12933-020-01090-9