Rocaglamide and silvestrol: a long story from anti-tumor to anti-coronavirus compounds.
Nat Prod Rep
; 38(1): 18-23, 2021 01 01.
Article
in English
| MEDLINE | ID: covidwho-662491
ABSTRACT
Covering up to the beginning of 2020Many natural substances have been transformed again and again with regard to their pharmaceutical-medical potential, including new members of a growing class of natural products, the flavaglines. Important representatives are rocaglamide and silvestrol, isolated from the Aglaia species, which are highlighted here. These products started as potential anti-tumor agents five decades ago and have recently proved to be very promising antiviral agents, especially against RNA viruses. Today they are discussed as potential starting compounds for developing drug candidates and therapeutics.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Antiviral Agents
/
Triterpenes
/
Benzofurans
/
Biological Products
/
Antineoplastic Agents
Limits:
Humans
Language:
English
Journal:
Nat Prod Rep
Journal subject:
Chemistry
Year:
2021
Document Type:
Article
Affiliation country:
D0np00024h
Similar
MEDLINE
...
LILACS
LIS