SARS-CoV2 infection in patients with solid organ transplant: five important questions Infección por SARS-CoV2 en pacientes con trasplante de órgano sólido: Cinco preguntas importantes / SARS-CoV2 infection in patients with solid organ transplant: five

ABSTRACT

Abstract There is a high expectation generated by the rapid expansion of SARS-CoV2 (Severe Acute Respiratory Syndrome related to Coronavirus 2), which is the etiological agent of the Coronavirus Infectious Disease 2019, COVID-19. As an emerging disease, little is known about its behavior in humans, which generates multiple questions when making decisions in clinical practice. So far, the strategies to face this pandemic are based on the experience of the countries that have been the epicenter of the infectious outbreak and on the evidence collected during the management of other past coronavirus infections such as (SARS-CoV in 2002 and MERS-CoV in 2012). The lack of unified and robust information has given rise to speculation and assumptions primarily related to the care and management of COVID-19 in populations considered at high risk of infection, such as chronically immunosuppressed patients after transplantation. Beyond giving the opinion from the authors, this narrative review tries to organize the documents published so far and to answer five of the most critical questions that arise every day during the management of transplant patients based on real data.